DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17121 and YDL114W

DIOPT Version :9

Sequence 1:	NP_651114.1	Gene:	CG17121 / 42721	FlyBaseID:	FBgn0039043	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_010169.1	Gene:	YDL114W / 851444	SGDID:	S000002272	Length:	308	Species:	Saccharomyces cerevisiae

Alignment Length:	246	Identity:	64/246 - (26%)
Similarity:	117/246 - (47%)	Gaps:	44/246 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 KHLLDY---LFALGLKEKDVSGK--VALVTGGGSGLGREICLELARRGCKLAVVDVNSKGCYETV 133
            |||.|:   :.:|......:..|  .||:|||.||||.|:..||:||..|:.|.|:.|...:..|
Yeast    15 KHLKDFPSVILSLPSYNPSILSKNATALITGGSSGLGFELAKELSRRINKVIVADIQSFPTFAQV 79

  Fly   134 ELLSKIPRCVAKAYKN------DVSSPRELQLMAAKVEKELGPVDILVNNASLMPMTSTPSLKSD 192
            |            |.|      |::|..|::.:...:|::.|.::|::|||.:..:.....:.:.
Yeast    80 E------------YNNIFYYQCDITSLDEIKNLKKAIERDHGNINIIINNAGVAHIKKLEHMTNK 132

  Fly   193 EIDTILQLNL-GSY-IMTTKEFLPKMINRKSGHLVAVNALAGLVPLPGAGIYTATKYGIEGFMES 255
            |::.::.:|| |:| |::|  |...||:.:.|.::.:.::.|.:.......|.|:|..:.||.:.
Yeast   133 EVEQLIDINLIGAYRIIST--FAEDMIDNREGFIINIASVLGELTPARLTSYGASKGAMIGFHKC 195

  Fly   256 LRAELR--LSDCDYVRTTVANAYLMRTSGDLPLLSDAGIAKS--YPGLPTP 302
            :....|  .::|:             .:|...||...|..|:  :..:|||
Yeast   196 MSRHFRSLSTECN-------------KTGIKTLLVCPGKIKTNMFIDVPTP 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17121	NP_651114.1	DltE	91..349	CDD:223377	59/226 (26%)
CG17121	NP_651114.1	NADB_Rossmann	94..338	CDD:304358	58/221 (26%)
YDL114W	NP_010169.1	17beta-HSDXI-like_SDR_c	40..282	CDD:187598	58/221 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	91	1.000	Domainoid score	I1741
eggNOG	1	0.900	-	-		E2759_KOG1201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	96	1.000	Inparanoid score	I1486
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000227
OrthoInspector	1	1.000	-	-		mtm9177
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24322
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.920