Protein Alignment CG17121 and si:dkey-221h15.4

DIOPT Version :10

• Sequence 1: NP_651114.1
• Gene: CG17121 / 42721
• FlyBaseID: FBgn0039043
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: NP_001373167.1
• Gene: si:dkey-221h15.4 / 563950
• ZFINID: ZDB-GENE-041014-340
• Length: 350
• Species: Danio rerio
• Alignment Length: 283
• Identity: 84/283 - (29%)
• Similarity: 140/283 - (49%)
• Gaps: 15/283 - (5%)

  Fly    63 LLPLVLLAVFLKHLLDYLFALGLKEKDVSGKVALVTGGGSGLGREICLELARRGCKLAVVDVNSK 127
            :..|:|.|||........|.:...:|||.|::.||||..:|:|:.|..||...|..|.:.|:||:
Zfish    16 IFELILGAVFYFFEAFVRFFIPRSKKDVEGEIVLVTGAANGIGKLIAKELGHYGATLVLWDINSE 80

  Fly   128 GCYETVELLSKIPRCVAKAYKNDVSSPRELQLMAAKVEKELGPVDILVNNASLMP-----MTSTP 187
            ...:|.:.|.::......||..|.|...|:..:|..|::|:|.|.||||||.::.     :.:..
Zfish    81 ALEKTAKELKQVLDVRVYAYTCDCSRRSEVYRVAEVVKREVGDVSILVNNAGMVSGKYTFLEAPD 145

  Fly   188 SLKSDEIDTILQLNLGSYIMTTKEFLPKMINRKSGHLVAVNALAGLVPLPGAGIYTATKYGIEGF 252
            ||    :|..|::|..::..|.|.|||.|:.:..|||:.|.....|..:.|...|.|:|.....|
Zfish   146 SL----VDRTLRVNAAAHFWTYKAFLPAMLEQDHGHLLCVACHGALFAMNGLADYCASKSAAVRF 206

  Fly   253 MESLRAELRLSDCDYVRTTVANAYLMRTSGDLPLLSDAGIAKSY--PGLPTPYVAEKIVKGVLLN 315
            .||:..||.:...:.::||:...||:.|:    :.......:.:  |.|...|.|::||..:|..
Zfish   207 AESIALELLVLKKEGIKTTIVCPYLINTN----MFGGCQTKRPFFLPVLEQRYAAKQIVDAILQE 267

  Fly   316 ERMVYVPKIFALSVWLLRLLPTK 338
            :..:.:|...:|.:.|..::|.|
Zfish   268 KMYLLLPSSLSLLMALKSVMPAK 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17121	NP_651114.1	Rossmann-fold NAD(P)(+)-binding proteins	94..338	CDD:473865	73/250 (29%)
si:dkey-221h15.4	NP_001373167.1	17beta-HSDXI-like_SDR_c	47..269	CDD:187598	69/229 (30%)