Protein Alignment CG17121 and hsd17b12

DIOPT Version :10

• Sequence 1: NP_651114.1
• Gene: CG17121 / 42721
• FlyBaseID: FBgn0039043
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: NP_001017234.1
• Gene: hsd17b12 / 549988
• XenbaseID: XB-GENE-945229
• Length: 320
• Species: Xenopus tropicalis
• Alignment Length: 254
• Identity: 63/254 - (24%)
• Similarity: 113/254 - (44%)
• Gaps: 35/254 - (13%)

  Fly    92 GKVALVTGGGSGLGREICLELARRGCKLAVVDVNSKGCYETVELLSKIPRCVAKAYKNDVSSPRE 156
            ||.|:|||...|:|:....|||:||..:.::..:.:...|..:.:.:..:...|....|...|.|
 Frog    56 GKWAVVTGATDGIGKAYAEELAKRGMNIVLISRSPEKLEEVAKQIKEKFKVETKIIAADFGKPTE 120

  Fly   157 LQLMAAKVEKELGPVDI--LVNNASLM---P--MTSTPSLKSDEIDTILQLNLGSYIMTTKEFLP 214
            :.   .::|..|..::|  ||||..:.   |  ....|.|: :.:|.::.:|:.|....|:..||
 Frog   121 IY---GRIESGLRDLEIGVLVNNVGVSYEHPEYFLEIPDLE-NTLDKMININITSVCQMTRLVLP 181

  Fly   215 KMINRKSGHLVAVNALAGLVPLPGAGIYTATKYGIEGFMESLRAELRLSDCD-------YVRTTV 272
            .|:.|..|.::.:::.:|:.|:|...:|:|||..::.|...|:||.|.....       ||.|.:
 Frog   182 GMLGRGRGVILNISSASGMYPVPLLTVYSATKAFVDFFSRGLQAEYRSKGVTVQSVLPFYVATKL 246

  Fly   273 ANAYLMRTSGDLPLLSDAGIAKSYPGLPTPYVAEKIVKGVLLNERMVYVPKIFALSVWL 331
            |.  :.:.:.|.|             .|..||...:....|..:...|:|  .|:..|:
 Frog   247 AK--IRKPTWDKP-------------SPETYVQSALNTVGLQTQTNGYLP--HAIMGWI 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17121	NP_651114.1	Rossmann-fold NAD(P)(+)-binding proteins	94..338	CDD:473865	61/252 (24%)
hsd17b12	NP_001017234.1	17beta-HSD1_like_SDR_c	56..297	CDD:187614	63/254 (25%)