Protein Alignment CG17121 and HSD17B11

DIOPT Version :9

• Sequence 1: NP_651114.1
• Gene: CG17121 / 42721
• FlyBaseID: FBgn0039043
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: NP_057329.3
• Gene: HSD17B11 / 51170
• HGNCID: 22960
• Length: 300
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 89/289 - (30%)
• Similarity: 144/289 - (49%)
• Gaps: 29/289 - (10%)

  Fly    61 LLLLPLVL---LAVFLKHLLDYLFALGLKEKDVSGKVALVTGGGSGLGREICLELARRGCKLAVV 122
            ||||||::   |..|:|     || :..:.|.|:|::.|:||.|.|:||....|.|:...||.:.
Human     8 LLLLPLLIVCSLESFVK-----LF-IPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLW 66

  Fly   123 DVNSKGCYETVELLSKIPRCVAK--AYKNDVSSPRELQLMAAKVEKELGPVDILVNNASLMPMTS 185
            |:|..|..||.   :|.....||  .:..|.|:..::...|.||:.|:|.|.||||||.::..:.
Human    67 DINKHGLEETA---AKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSD 128

  Fly   186 TPSLKSDEIDTILQLNLGSYIMTTKEFLPKMINRKSGHLVAVNALAGLVPLPGAGIYTATKYGIE 250
            ..:.:..:|:...::|:.::..|||.|||.|.....||:|.|.:.||.|.:|....|.::|:...
Human   129 LFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAV 193

  Fly   251 GFMESLRAELRLSDCDYVRTTVANAYLMRTSGDLPLLSDAGIAKS-----YPGLPTPYVAEKIVK 310
            ||.::|..||.......|:||..          .|...:.|..|:     .|.|....|..:::.
Human   194 GFHKTLTDELAALQITGVKTTCL----------CPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMH 248

  Fly   311 GVLLNERMVYVPKIFALSVWLLRLLPTKW 339
            |:|..::|:::|...|....|.|:||.::
Human   249 GILTEQKMIFIPSSIAFLTTLERILPERF 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17121	NP_651114.1	DltE	91..349	CDD:223377	76/256 (30%)
		NADB_Rossmann	94..338	CDD:304358	75/250 (30%)
HSD17B11	NP_057329.3	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	75/251 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1373099at2759
OrthoFinder	1	1.000	-	-		FOG0000227
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24322
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920