Protein Alignment CG17121 and Decr2

DIOPT Version :10

• Sequence 1: NP_651114.1
• Gene: CG17121 / 42721
• FlyBaseID: FBgn0039043
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: NP_001398237.1
• Gene: Decr2 / 26378
• MGIID: 1347059
• Length: 351
• Species: Mus musculus
• Alignment Length: 291
• Identity: 73/291 - (25%)
• Similarity: 109/291 - (37%)
• Gaps: 87/291 - (29%)

  Fly    79 YLFALGLKEKDVSGKVALVTGGGSGLGREICLELARRGCKLAVVDVNSKGCYETVELLSKI---- 139
            :||...|    :..|||.:||||||:|..|.....|.||...:|   .:...:......|:
Mouse    19 HLFCPDL----LQDKVAFITGGGSGIGFRIAEIFMRHGCHTVIV---GRSLQKVTTAAKKLVAAT 76

  Fly   140 -PRCVAKAYKNDVSSPRELQLMAAKVEKELGPVDILVNNAS---LMPMT--STPSLKS-DEIDTI 197
             .||:..:.  ||..|.|:.....:..:|.|.::||:|.|:   |.|.:  |..:.|: .:||||
Mouse    77 GKRCLPLSM--DVRVPPEVMTAVDQALQEFGKINILINCAAGNFLCPASALSFNAFKTVVDIDTI 139

  Fly   198 LQLNLGSY---------------IMTTKEFLPKMINRKSG-----------HL--------VAVN 228
            ...|:.|.               |..|.....:::...:|           ||        :.||
Mouse   140 GTFNVSSVLYKKFFRDHGGVIVNITATLSMRGQVLQLHAGAAKAAVDAMTRHLAVEWGPQNIRVN 204

  Fly   229 ALAGLVPLPGAGIYTATKYGIEGFMESLRAELRLSDCDY---------VRTTVANAYLMRTSGDL 284
            :||     |||      ..|.|| :..||.....|...:         .:|.:|::.|...|
Mouse   205 SLA-----PGA------ISGTEG-LRRLRGSNASSKLKHFSNPIPRLGTKTEIAHSVLYLAS--- 254

  Fly   285 PLLS--DAGIAKSYP-------GLPTPYVAE 306
            ||.|  ....::.||       |....||||
Mouse   255 PLASYVSGESSRGYPPSSSLKIGSHVHYVAE 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17121	NP_651114.1	Rossmann-fold NAD(P)(+)-binding proteins	94..338	CDD:473865	69/276 (25%)
Decr2	NP_001398237.1	TER_DECR_SDR_a	26..263	CDD:187627	63/256 (25%)
		HYR	<255..296	CDD:460572	10/31 (32%)