Protein Alignment CG13833 and DHRS3

DIOPT Version :10

• Sequence 1: NP_651111.1
• Gene: CG13833 / 42718
• FlyBaseID: FBgn0039040
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_004744.2
• Gene: DHRS3 / 9249
• HGNCID: 17693
• Length: 302
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 79/285 - (27%)
• Similarity: 148/285 - (51%)
• Gaps: 18/285 - (6%)

  Fly    19 IGLAAITPL----LILVALLGRLI-AKLCWCSAPKSIAGEVAVVTGAGHGLGRAISLELAKKGCH 78
            :|...:.||    |::.|.:|.:: |||      :.::.|..::||.|.|:||.::.|.|::|..
Human     6 LGALVMFPLQMIYLVVKAAVGLVLPAKL------RDLSRENVLITGGGRGIGRQLAREFAERGAR 64

  Fly    79 -IAVVDINVSGAEDTVKQIQDIYKVRAKAYKANVTNYDDLVELNSKVVEEMGPVTVLVNNAGVMM 142
             |.:........::|.::|:.: ......:..:|.|.:::.:....|.|::|.:|:|||||.|:.
Human    65 KIVLWGRTEKCLKETTEEIRQM-GTECHYFICDVGNREEVYQTAKAVREKVGDITILVNNAAVVH 128

  Fly   143 HRNMFNPDPADVQLMINVNLTSHFWTKLVFLPKMKELRKGFIVTISSLAGVFPLPYSATYTTTKS 207
            .:::.:.|...:....::|....|||...|||:|.||:.|.||.::|:..:..:|.:..|.|:|:
Human   129 GKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKA 193

  Fly   208 GALAHMRTLRMELDLENQKDIHVTTVLPSFLRTNSDVTQLTHTIGFGDVYPLFTGEEVAQRIVAG 272
            .|.|.|.:|  .|.|.:...:..|||||  ..|::::.| ...:.|.:::|....|.||:|.|..
Human   194 SAFAFMESL--TLGLLDCPGVSATTVLP--FHTSTEMFQ-GMRVRFPNLFPPLKPETVARRTVEA 253

  Fly   273 MVRGEAEITVPGMACLLYRVILILP 297
            :...:|.:.:|.....|..:..|||
Human   254 VQLNQALLLLPWTMHALVILKSILP 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13833	NP_651111.1	YqjQ	49..305	CDD:440069	70/250 (28%)
DHRS3	NP_004744.2	17beta-HSDXI-like_SDR_c	53..281	CDD:187598	63/232 (27%)