DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13833 and TDA5

DIOPT Version :9

Sequence 1:	NP_651111.1	Gene:	CG13833 / 42718	FlyBaseID:	FBgn0039040	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_013530.1	Gene:	TDA5 / 851146	SGDID:	S000004418	Length:	326	Species:	Saccharomyces cerevisiae

Alignment Length:	336	Identity:	77/336 - (22%)
Similarity:	130/336 - (38%)	Gaps:	77/336 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 ITPLL---ILVALLGR---------------------LIA--------KLCWCSAPKSIAGEVAV 56
            :.|||   :||||:.|                     |||        ::.|.|. :.....:.:
Yeast    11 VLPLLRYPLLVALVLRWSLSDSISICLTIYTLLINAFLIANSYIKRSGQVAWKSL-REFKNGIVL 74

  Fly    57 VTGAGHGLGRAISLELAKKGCHIAVVDINV-------SGAEDTVKQIQDIYKVRA------KAYK 108
            :||...||||||..:|.:...::.::::::       :..:|.:..:.|..:|.|      :.||
Yeast    75 ITGGSKGLGRAIVSQLLQDYSNLTILNVDICPSSVRNTRVKDLICDLSDDEEVAALLNLLKRKYK 139

  Fly   109 ANVTNYDDLVELNSKVVEEMGPVTVLVNNAGVMMHRNMFN---PDPADVQLMINVNLTSHFWTKL 170
                                ..:.::||||||..:...||   .|..|....||......|..:|
Yeast   140 --------------------NEIRLIVNNAGVRANFTGFNGMERDNLDKIFKINTFAPLQFIQEL 184

  Fly   171 VFLPKMKELRKGFIVTISSLAGVFPLPYSATYTTTKSGALAHMRTLRMELDLENQKDIHVTTVLP 235
            .  |.....|:.:||.|:|:.|:......|.|..:|:..:|..::...||..|..::|....|.|
Yeast   185 A--PSRHSTRQCYIVNIASILGILTPAKVAAYAASKAALIAFHQSYSFELQNEGVRNIRTLLVTP 247

  Fly   236 SFLRTNSDVTQLTHTIGFGDVYPLFTGEEVAQRIVAGMVRGE-AEITVPGMACLLYRVILILPAD 299
            ..|.|............|..|..:.|   :|.:||.....|: .::..| ..|....:::.:|..
Yeast   248 GQLNTEMFAGFKPPRQFFAPVIDITT---LAAKIVRYCELGQRGQLNEP-FYCSFAHLLMCVPYS 308

  Fly   300 WQDRIILLFSR 310
            .| ||:..|||
Yeast   309 LQ-RIVRSFSR 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13833	NP_651111.1	adh_short	53..241	CDD:278532	47/203 (23%)
CG13833	NP_651111.1	NADB_Rossmann	54..297	CDD:304358	57/259 (22%)
TDA5	NP_013530.1	NADB_Rossmann	72..309	CDD:419666	58/262 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9177
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24322
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910