DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13833 and Hsdl2

DIOPT Version :9

Sequence 1:	NP_651111.1	Gene:	CG13833 / 42718	FlyBaseID:	FBgn0039040	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_077217.2	Gene:	Hsdl2 / 72479	MGIID:	1919729	Length:	490	Species:	Mus musculus

Alignment Length:	173	Identity:	52/173 - (30%)
Similarity:	81/173 - (46%)	Gaps:	20/173 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 IAGEVAVVTGAGHGLGRAISLELAKKGCHIAVVDINVSGAEDTVKQ---IQDIYKVRAKAYKAN- 110
            :||....:|||..|:|:||:|:.||.|.:|.:      .|:.|.|.   :..||....:...|.
Mouse     8 LAGCTVFITGASRGIGKAIALKAAKDGANIVI------AAKTTQKHPKLLGTIYTAAEEIEAAGG 66

  Fly   111 -----VTNYDDLVELNS---KVVEEMGPVTVLVNNAGVMMHRNMFNPDPADVQLMINVNLTSHFW 167
                 |.:..|..::||   |.||:.|.:.:|||||..:...|..:.....|.||:|||....:.
Mouse    67 TALPCVVDVRDEQQINSAVEKAVEKFGGIDILVNNASAISLTNTLDTPTKRVDLMMNVNTRGTYL 131

  Fly   168 TKLVFLPKMKELRKGFIVTISSLAGVFPLPYS--ATYTTTKSG 208
            |....:|.:|:.:.|.|:.:|....:.||.:.  ..||..|.|
Mouse   132 TSKACIPFLKKSKVGHILNLSPPLNLNPLWFKQHCAYTIAKYG 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13833	NP_651111.1	adh_short	53..241	CDD:278532	50/170 (29%)
CG13833	NP_651111.1	NADB_Rossmann	54..297	CDD:304358	50/169 (30%)
Hsdl2	NP_077217.2	HSDL2_SDR_c	8..248	CDD:187663	52/173 (30%)
		adh_short	12..197	CDD:278532	50/169 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	282..370
		SCP2	390..483	CDD:280250
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1809
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950