Protein Alignment CG13833 and Hsd17b12

DIOPT Version :10

• Sequence 1: NP_651111.1
• Gene: CG13833 / 42718
• FlyBaseID: FBgn0039040
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_062631.1
• Gene: Hsd17b12 / 56348
• MGIID: 1926967
• Length: 312
• Species: Mus musculus
• Alignment Length: 306
• Identity: 76/306 - (24%)
• Similarity: 128/306 - (41%)
• Gaps: 58/306 - (18%)

  Fly    43 WCSAPKSIA----GEVAVVTGAGHGLGRAISLELAKKGCHIAVVDINVSGAEDTVKQIQDIYKVR 103
            ||...:::.    ||.|||||...|:|:|.:.||||:|..|.:    :|.::|.:.|:.:..|.:
Mouse    37 WCVGNEALVGPRLGEWAVVTGGTDGIGKAYAEELAKRGMKIVL----ISRSQDKLNQVSNNIKEK 97

  Fly   104 AKAYKANVTNYDDLVELNSKVVEEMG--PVTVLVNNAGVMMHRNMFNPDPAD----VQLMINVNL 162
            .......:.....|.::..|:...:.  .:.|||||.|:......:..:..|    ::.:||:|:
Mouse    98 FNVETRTIAVDFSLDDIYDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININV 162

  Fly   163 TSHFWTKLVFLPKMKELRKGFIVTISSLAGVFPLPYSATYTTTKSGALAHMRTLRMELDLENQKD 227
            .|......:.||.|.|..||.|:.|||.:|:.|:|....|:.||:......:.|..|.   ..|.
Mouse   163 LSVCKVTRLVLPGMVERSKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEY---KSKG 224

  Fly   228 IHVTTVLPSFLRT---------------NSDVTQLTHTIGFGDVYPLFTGEEVAQRIVAGMVRGE 277
            |.|.:|:|..:.|               .:.|.....|:|.             |....|.|
Mouse   225 IFVQSVMPYLVATKLAKIQKPTLDKPSAETFVKSAIKTVGL-------------QTRTTGYV--- 273

  Fly   278 AEITVPGMACLLYRVILILPADWQDRIILLFS---RNKFKKLRDEH 320
                   :..|:..:..|:|.....:||:.||   ||::.|.|.::
Mouse   274 -------IHSLMGSINSIMPRWMYFKIIMGFSKSLRNRYLKKRKKN 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13833	NP_651111.1	YqjQ	49..305	CDD:440069	66/280 (24%)
Hsd17b12	NP_062631.1	Rossmann-fold NAD(P)(+)-binding proteins	<4..>83	CDD:473865	19/49 (39%)
		17beta-HSD1_like_SDR_c	50..288	CDD:187614	66/267 (25%)
		Di-lysine motif. /evidence=ECO:0000250	308..312		1/3 (33%)