DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13833 and hsd17b13

DIOPT Version :9

Sequence 1:	NP_651111.1	Gene:	CG13833 / 42718	FlyBaseID:	FBgn0039040	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001011240.1	Gene:	hsd17b13 / 496682	XenbaseID:	XB-GENE-995635	Length:	300	Species:	Xenopus tropicalis

Alignment Length:	267	Identity:	80/267 - (29%)
Similarity:	138/267 - (51%)	Gaps:	19/267 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 KSIAGEVAVVTGAGHGLGRAISLELAKKGCHIAVVDINVSGAEDTVKQIQDIYKVRAKAYK--AN 110
            ||:||.:.::||:|||:||..:||.||....:.:.|||..|.|:|..:.:   |:.|.||.  .:
Frog    32 KSVAGNIVLITGSGHGIGRRTALEFAKHESILVLWDINQKGVEETADECR---KLGATAYAFVVD 93

  Fly   111 VTNYDDLVELNSKVVEEMGPVTVLVNNAGVMMHRNMFNPDPADVQLMINVNLTSHFWTKLVFLPK 175
            .:..:|:.....||.:::|.|.:|:|||||:............::...:||:.:||||...||..
Frog    94 CSTRNDIYRCAEKVKQDIGDVDILINNAGVVFGTEFLKLQDHQIEKTFSVNILAHFWTTKSFLSA 158

  Fly   176 MKELRKGFIVTISSLAGVFPLPYSATYTTTKSGALAHMRTLRMELDLENQKDIHVTTVLPSFLRT 240
            |.:..:|.|||::|:||...:||...|..:|.|.:....:|..||.|..:..:..|.:.|.|:.|
Frog   159 MMKKDRGHIVTVASIAGQLGVPYLVDYCASKFGLVGFHESLTSELKLLGKDGVKTTCLCPVFVNT 223

  Fly   241 NSDVTQLTHTIGFGDVYPLFTGEEVAQRIVAGMVRGEAEITVPGMACLLYRVIL--ILPADWQDR 303
            .......|.      |:|:...|:|.:.::.|::..:..|.||  :.:.|.:|:  .||    :|
Frog   224 GFVQNPSTR------VWPVLKTEDVVKCLMEGILTNKKMIIVP--SSVKYSLIMNQFLP----ER 276

  Fly   304 IILLFSR 310
            :|...::
Frog   277 VIATMTK 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13833	NP_651111.1	adh_short	53..241	CDD:278532	60/189 (32%)
CG13833	NP_651111.1	NADB_Rossmann	54..297	CDD:304358	72/246 (29%)
hsd17b13	NP_001011240.1	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	74/253 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1373099at2759
OrthoFinder	1	1.000	-	-		FOG0000227
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24322
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020