DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13833 and Hsd17b13

DIOPT Version :9

Sequence 1:	NP_651111.1	Gene:	CG13833 / 42718	FlyBaseID:	FBgn0039040	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_932147.2	Gene:	Hsd17b13 / 243168	MGIID:	2140804	Length:	304	Species:	Mus musculus

Alignment Length:	236	Identity:	69/236 - (29%)
Similarity:	118/236 - (50%)	Gaps:	7/236 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 KSIAGEVAVVTGAGHGLGRAISLELAKKGCHIAVVDINVSGAEDTVKQIQDIYKVRAKAYKANVT 112
            ||:.|:..::||||||:||..:.|.||:...:.:.|||..|.|:|..:.:.:..| ...:..:.:
Mouse    32 KSVTGQTVLITGAGHGIGRLTAYEFAKQKSRLVLWDINKRGVEETADKCRKLGAV-VHVFVVDCS 95

  Fly   113 NYDDLVELNSKVVEEMGPVTVLVNNAGVMMHRNMFNPDPADVQLMINVNLTSHFWTKLVFLPKMK 177
            |..::.....:|..|:|.|.::|||||.:...::.:....::.....||:..|||.....||.|.
Mouse    96 NRAEIYNSVDQVKREVGDVEIVVNNAGAIYPADLLSAKDEEITKTFEVNILGHFWIIKALLPSML 160

  Fly   178 ELRKGFIVTISSLAGVFPLPYSATYTTTKSGALAHMRTLRMELDLENQKDIHVTTVLPSFLRTNS 242
            ....|.|||::|:.|...:||...|.::|..|:...|.|..|||...:..|..:.:.|.|:.|..
Mouse   161 RRNSGHIVTVASVCGHGVIPYLIPYCSSKFAAVGFHRALTAELDTLGKTGIQTSCLCPVFVNTGF 225

  Fly   243 DVTQLTHTIGFGDVYPLFTGEEVAQRIVAGMVRGEAEITVP 283
            .....|.      ::|:...||||:.::.|::..:..|.||
Mouse   226 TKNPSTR------LWPVLEPEEVARSLINGILTNKKMIFVP 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13833	NP_651111.1	adh_short	53..241	CDD:278532	55/187 (29%)
CG13833	NP_651111.1	NADB_Rossmann	54..297	CDD:304358	66/230 (29%)
Hsd17b13	NP_932147.2	adh_short	37..228	CDD:278532	56/191 (29%)
		17beta-HSDXI-like_SDR_c	38..269	CDD:187598	66/230 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	276..304
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1373099at2759
OrthoFinder	1	1.000	-	-		FOG0000227
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24322
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920