DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13833 and dhs-29

DIOPT Version :9

Sequence 1:	NP_651111.1	Gene:	CG13833 / 42718	FlyBaseID:	FBgn0039040	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_509294.1	Gene:	dhs-29 / 181027	WormBaseID:	WBGene00000992	Length:	427	Species:	Caenorhabditis elegans

Alignment Length:	243	Identity:	65/243 - (26%)
Similarity:	123/243 - (50%)	Gaps:	5/243 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 KSIAGEVAVVTGAGHGLGRAISLELAKKGCHIAVVDINVSGAEDTVKQIQDIYKVRAKAYKANVT 112
            ||:.|:..::||.|.|||||::|:.||:...:|::|:|..|..:|||.|.....: ||.:..:::
Worm    37 KSVQGQTVIITGGGSGLGRAMALDFAKRKAKVAIIDVNKEGGLETVKTIAAEGNM-AKFWYCDIS 100

  Fly   113 NYDDLVELNSKVVEEMGPVTVLVNNAGVMMHRNMFNPDPADVQLMINVNLTSHFWTKLVFLPKMK 177
            :.|::.:...::.:..|.|.:::.||.::...:........::..::||:.....|...|||||:
Worm   101 DVDNMKKTAKEIEDTFGDVNIVICNAAILSFTSFMEISDELLRKCLDVNIFGTINTIRAFLPKME 165

  Fly   178 ELRKGFIVTISSLAGVFPLPYSATYTTTKSGALAHMRTLRMELDLENQKDIHVTTVLPSFLRTNS 242
            ....|.||.:.|:||........:|.|:|......|.:|:|||.....:.|..||:.|.|.||..
Worm   166 TKNDGHIVCVCSIAGWSGETMGLSYCTSKFAVRGAMESLQMELRDRGLEGIKTTTLYPYFARTPM 230

  Fly   243 DV-TQLTHTIGFGDVYPLFTGEEVAQRIVAGMVRGEAEITVPGMACLL 289
            .: ..:..|..:   :|..:....::|:|..:::.:....||....|:
Worm   231 ILENNMRPTCTW---FPFMSIRSCSKRMVDSILKEKVHAFVPSYITLI 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13833	NP_651111.1	adh_short	53..241	CDD:278532	54/187 (29%)
CG13833	NP_651111.1	NADB_Rossmann	54..297	CDD:304358	62/237 (26%)
dhs-29	NP_509294.1	adh_short	42..230	CDD:278532	55/188 (29%)
		NADB_Rossmann	43..281	CDD:304358	62/237 (26%)
		DUF4499	322..416	CDD:291595
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1373099at2759
OrthoFinder	1	1.000	-	-		FOG0000227
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24322
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.880