Protein Alignment lmd and ACE2

DIOPT Version :10

• Sequence 1: NP_732811.1
• Gene: lmd / 42717
• FlyBaseID: FBgn0039039
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_013232.1
• Gene: ACE2 / 850822
• SGDID: S000004121
• Length: 770
• Species: Saccharomyces cerevisiae
• Alignment Length: 587
• Identity: 123/587 - (20%)
• Similarity: 195/587 - (33%)
• Gaps: 172/587 - (29%)

  Fly   105 QQQDSDQDDIVCAAAENTGMP----------YQQGQ-------YTQLNREDIFRFEPEDI--ARL 150
            ::|:.....:|..|..:...|          .|.|:       .|..:....::|.|..:  .|:
Yeast   231 EEQEEVAQKLVSGATNSNSKPGSPVILKTPAMQNGRMKDNAIIVTTNSANGGYQFPPPTLISPRM 295

  Fly   151 TGES--ELPGMLQHPQTPYTPYTPYTPYTPCSAQNSQY-------AVQPANDSINLDIDYFNYDE 206
            :..|  ..|....|.|. |...:|.:......:.||.|       :..|.|.::|||...:| |.
Yeast   296 SNTSINGSPSRKYHRQR-YPNKSPESNGLNLFSSNSGYLRDSELLSFSPQNYNLNLDGLTYN-DH 358

  Fly   207 INCQSKNQSPCSSPHLDAWLNFNLGEISAAASSSAASPKLGNVFEEQVKEEASPAKLP------- 264
            .|...||.:...:...|                        |:|  ::.|:.||..|.
Yeast   359 NNTSDKNNNDKKNSTGD------------------------NIF--RLFEKTSPGGLSISPRING 397

  Fly   265 -SMNSTF--GTPKCIPMCASNYEDYANLYQQGSGYSTENYHNNMAQVVEKPNREHKAIWTIDELD 326
             |:.|.|  ||.|      |..:.||      :|..|..     .|:.....:....:.|:..:.
Yeast   398 NSLRSPFLVGTDK------SRDDRYA------AGTFTPR-----TQLSPIHKKRESVVSTVSTIS 445

  Fly   327 ELMLGEQQQFLQHHLQQQHLQEQQEQLHQPHGQEQQTQNCKDDLVNYLSDEFIKAEEFRSLDSDD 391
            :                  ||:..|.:|..:.|....:|     .|.|:...:......|.::..
Yeast   446 Q------------------LQDDTEPIHMRNTQNPTLRN-----ANALASSSVLPPIPGSSNNTP 487

  Fly   392 DENYNEEEDDLDNDVFA-PPAESDPK-----------PDSTCCDPEAEPENEVIPLICRWTGCDE 444
            .:|...::     .||. .|.::.||           ||.|      :.:.|:...|...:.|:.
Yeast   488 IKNSLPQK-----HVFQHTPVKAPPKNGSNLAPLLNAPDLT------DHQLEIKTPIRNNSHCEV 541

  Fly   445 EFPHQQAFVEHIEKCHVDVRKGEDFSCFWLDCPRRYKPFNARYKL----------LIHMRVHSGE 499
            |...|...|.|      |:.|...... ....|....|.....|:          .|...|.  |
Yeast   542 ESYPQVPPVTH------DIHKSPTLHS-TSPLPDEIIPRTTPMKITKKPTTLPPGTIDQYVK--E 597

  Fly   500 KPNK---CPFPGCNKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKHQRTHYDTKP 561
            .|:|   |.:|.|||.|.|..|::.|.::|..:|||.|.:.||.|||..:.|..:|:.:| :.|.
Yeast   598 LPDKLFECLYPNCNKVFKRRYNIRSHIQTHLQDRPYSCDFPGCTKAFVRNHDLIRHKISH-NAKK 661

  Fly   562 YACQLPGCTKRYTDPSSLRKHVKNHALRNANGQLRRKSAGGASVPPS------GPKKAAKTRRHS 620
            |.|.   |.||:....:|..|           :.|....||..:..|      .|||:.....|.
Yeast   662 YICP---CGKRFNREDALMVH-----------RSRMICTGGKKLEHSINKKLTSPKKSLLDSPHD 712

  Fly   621 ES 622
            .|
Yeast   713 TS 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lmd	NP_732811.1	SFP1	<493..585	CDD:227516	34/94 (36%)
		C2H2 Zn finger	504..526	CDD:275368	9/21 (43%)
		C2H2 Zn finger	534..556	CDD:275368	8/21 (38%)
		C2H2 Zn finger	564..586	CDD:275368	6/21 (29%)
ACE2	NP_013232.1	COG5048	176..683	CDD:227381	114/554 (21%)
		C2H2 Zn finger	605..627	CDD:275368	9/21 (43%)
		C2H2 Zn finger	635..657	CDD:275368	8/21 (38%)
		C2H2 Zn finger	664..680	CDD:275368	6/29 (21%)