Protein Alignment lmd and Glis2

DIOPT Version :10

• Sequence 1: NP_732811.1
• Gene: lmd / 42717
• FlyBaseID: FBgn0039039
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: XP_036016078.1
• Gene: Glis2 / 83396
• MGIID: 1932535
• Length: 548
• Species: Mus musculus
• Alignment Length: 473
• Identity: 144/473 - (30%)
• Similarity: 192/473 - (40%)
• Gaps: 123/473 - (26%)

  Fly   410 PAESD-PKPDSTCCDPEAEPENEVIPLICRWTGCDEEFPHQQAFVEHIEKCHVDVRKGEDFSCFW 473
            ||.|. |.|...|..||.....:   |:|||..|::.|...|..|:|:...||...:...:.|.|
Mouse   172 PASSFLPPPKDKCLSPELPLAKQ---LVCRWAKCNQLFELLQDLVDHVNDHHVKPEQDARYCCHW 233

  Fly   474 LDCPRRYKPFNARYKLLIHMRVHSGEKPNKCPFPGCNKAFSRLENLKIHQRSHTGERPYGCQYKG 538
            ..|.|..:.||||||:|||:|.|:.|||::|  |.|||:||||||||||.||||||:||.|.|:|
Mouse   234 EGCARHGRGFNARYKMLIHIRTHTNEKPHRC--PTCNKSFSRLENLKIHNRSHTGEKPYVCPYEG 296

  Fly   539 CLKAFSNSSDRAKHQRTHYDTKPYACQLPGCTKRYTDPSSLRKHVKNHALRNANG-----QLRRK 598
            |.|.:||||||.||.||||..|||.|::|||.||||||||||||:|.|....::.     |||..
Mouse   297 CNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPP 361

  Fly   599 SAGGASVPPSGP-KKAAKTRRHSESALVQRGVGAGVGVAVPSAPGDQRQHRSNSCSEALLLQQHQ 662
            .......|.||. ...|:....:.:||.......|:.:.:|..|.|         ..||.
Mouse   362 PKPPLPTPDSGSYVSGAQIIIPNPAALFGGPSLPGLPLPLPPGPLD---------LSALA----- 412

  Fly   663 QQQQQQQQQQKQHQPENERTTDRSNCGTGVAANNNSMNFNELSNCIVIIEHNQSGGPAGPATLAT 727
                                     ||.|                      ...||..||....:
Mouse   413 -------------------------CGNG----------------------GGGGGGIGPGLPGS 430

  Fly   728 ATATTTA-----TATYGNGNMAPAPETEVLSVCSGGGSSNSNSNNNRYNANI-----------NQ 776
            ......|     .:.:|.|.:. .|...:|     |||:.|.:...:...::           ..
Mouse   431 VLPLNLAKNPLLPSPFGAGGLG-LPVVSLL-----GGSAGSKAEGEKGRGSVPARVLGLEDHKTP 489

  Fly   777 LSELEQLLTTAKPTGTPAASANGISLANNNGRANGDSKCHLSEFVSFEYVTKYLTDVYEPQCKSP 841
            |...|:..:...|.|.|......:.|:..|..|:                        .|:..:|
Mouse   490 LERTERSRSRPSPDGLPLLPGTVLDLSTGNSAAS------------------------SPEVLTP 530

  Fly   842 Q----PPANFHLQPEFDN 855
            .    ||.:..|:|...|
Mouse   531 GWVVIPPGSVLLKPAVVN 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lmd	NP_732811.1	SFP1	<493..585	CDD:227516	64/91 (70%)
		C2H2 Zn finger	504..526	CDD:275368	16/21 (76%)
		C2H2 Zn finger	534..556	CDD:275368	14/21 (67%)
		C2H2 Zn finger	564..586	CDD:275368	17/21 (81%)
Glis2	XP_036016078.1	C2H2 Zn finger	240..256	CDD:275368	10/15 (67%)
		COG5048	260..>354	CDD:227381	63/95 (66%)
		C2H2 Zn finger	264..284	CDD:275368	16/21 (76%)
		C2H2 Zn finger	292..314	CDD:275368	14/21 (67%)
		C2H2 Zn finger	322..344	CDD:275368	17/21 (81%)