DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lmd and ELF6

DIOPT Version :9

Sequence 1:	NP_732811.1	Gene:	lmd / 42717	FlyBaseID:	FBgn0039039	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	NP_196044.2	Gene:	ELF6 / 830303	AraportID:	AT5G04240	Length:	1340	Species:	Arabidopsis thaliana

Alignment Length:	371	Identity:	77/371 - (20%)
Similarity:	129/371 - (34%)	Gaps:	93/371 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 NVFEEQVKEEASPAKLPSMNSTFGTPKCIPMCASNYEDYANLYQQGSGYSTENYHNNMAQVVEKP 312
            |:.:||..:...|.:   ..:.||.                 ::|..|....:...|:...:..
plant  1018 NIEDEQQSQIVKPTQ---REAVFGD-----------------HEQVEGAEAVSTRENLCSEIIL- 1061

  Fly   313 NREHKAIWTIDELDELMLGEQQQFLQHHLQQQHLQEQQEQLHQPHGQEQQTQNCKDDLVNYLSDE 377
            :.||.:.....|:.::....:...:......:.| |..:.|...:|.|..:..     :..|:||
plant  1062 HTEHSSAHVGMEIPDINTASENLVVDMTHDGEPL-ESSDILSSSNGDEASSNG-----LQVLNDE 1120

  Fly   378 FI---------------------KAEEFRSLDSDDDENYNEEEDDLDNDVFAPPAE---SDPKPD 418
            ..                     :|::.|.::|:.:.|.|.|.   .......|.|   |..|..
plant  1121 LSMESEVSSSENTEVIEAPNSMGEAKKKRKIESESETNDNPES---SIGFIRSPCEGLRSRGKRK 1182

  Fly   419 STC---------CDPEAEP---ENEVIPLICRWTGCDEEFPHQQAFVEHIEKCHVDVRKGEDFSC 471
            :||         .|.|.:|   ..:..|..|..:. .:|.|    ...|..:|:::..|
plant  1183 ATCETSLKHTETSDEEKKPIAKRLKKTPKACSGSR-QQEVP----TTTHPNRCYLEGCK------ 1236

  Fly   472 FWLDCPRRYKPFNARYKLLIHMRVHSGEKPNKCPFPGCNKAFSRLENLKIHQRSHTGERPYGCQY 536
                     ..|.::.||..|.|       |:|...||.|.|...:.|.:|||.|..|||:.|.:
plant  1237 ---------MTFESKAKLQTHKR-------NRCTHEGCGKKFRAHKYLVLHQRVHKDERPFECSW 1285

  Fly   537 KGCLKAFSNSSDRAKHQRTHYDTKPYACQLPGCTKRYTDPSSLRKH 582
            |||...|.....|.:|.|.|...:||.|::.||...:...|...:|
plant  1286 KGCSMTFKWQWARTEHLRLHTGERPYICKVDGCGLSFRFVSDYSRH 1331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lmd	NP_732811.1	zf-H2C2_2	489..515	CDD:290200	9/25 (36%)
		C2H2 Zn finger	504..526	CDD:275368	9/21 (43%)
		C2H2 Zn finger	534..556	CDD:275368	8/21 (38%)
		C2H2 Zn finger	564..586	CDD:275368	5/19 (26%)
ELF6	NP_196044.2	JmjN	17..50	CDD:396793
		JmjC	292..411	CDD:396791
		C2H2 Zn finger	1230..1255	CDD:275368	9/46 (20%)
		C2H2 Zn finger	1253..1275	CDD:275368	9/21 (43%)
		C2H2 Zn finger	1283..1305	CDD:275368	8/21 (38%)
		C2H2 Zn finger	1313..1333	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000