Protein Alignment lmd and SP6

DIOPT Version :10

• Sequence 1: NP_732811.1
• Gene: lmd / 42717
• FlyBaseID: FBgn0039039
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_954871.1
• Gene: SP6 / 80320
• HGNCID: 14530
• Length: 376
• Species: Homo sapiens
• Alignment Length: 135
• Identity: 46/135 - (34%)
• Similarity: 72/135 - (53%)
• Gaps: 18/135 - (13%)

  Fly   498 GEKP--NKCPFPGCNKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKHQRTHYDTK 560
            |:|.  :.|..|||.||:::..:||.|.|.|:|:||:.|.:..|.|.|:.|.:..:|.:||..||
Human   248 GKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTK 312

  Fly   561 PYACQLPGCTKRYTDPSSLRKHVKNH------ALRNANGQLRRKSAGGASVPPSGPKKAAKTRRH 619
            .:.|.:  |::.:.....|.||:|.|      |...|:|:   ..||||..||.|     |.:|.
Human   313 KFPCAV--CSRVFMRSDHLAKHMKTHEGAKEEAAGAASGE---GKAGGAVEPPGG-----KGKRE 367

  Fly   620 SESAL 624
            :|.::
Human   368 AEGSV 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lmd	NP_732811.1	SFP1	<493..585	CDD:227516	31/88 (35%)
		C2H2 Zn finger	504..526	CDD:275368	10/21 (48%)
		C2H2 Zn finger	534..556	CDD:275368	6/21 (29%)
		C2H2 Zn finger	564..586	CDD:275368	6/21 (29%)
SP6	NP_954871.1	SP6_N	1..255	CDD:411693	2/6 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..70
		9aaTAD. /evidence=ECO:0000269|PubMed:31375868	118..126
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	167..223
		C2H2 Zn finger	259..278	CDD:275368	9/18 (50%)
		COG5048	<261..>336	CDD:227381	27/76 (36%)
		C2H2 Zn finger	286..308	CDD:275368	6/21 (29%)
		C2H2 Zn finger	316..336	CDD:275368	6/21 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	333..376		15/48 (31%)