Protein Alignment lmd and Glis3

DIOPT Version :10

• Sequence 1: NP_732811.1
• Gene: lmd / 42717
• FlyBaseID: FBgn0039039
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_001419411.1
• Gene: Glis3 / 680671
• RGDID: 1565505
• Length: 929
• Species: Rattus norvegicus
• Alignment Length: 883
• Identity: 255/883 - (28%)
• Similarity: 332/883 - (37%)
• Gaps: 328/883 - (37%)

  Fly     4 SLKTSQSGGMYVKTSSISGISSISGKEAASCYGGFMSPPLSANITANNGEREMFRVPGAKVETNE 68
            ||..||| .:.||            :|.:..|.||  |.||:|.::.||
  Rat   213 SLTESQS-ALSVK------------QEWSQSYRGF--PSLSSNHSSQNG---------------- 246

  Fly    69 SYACGELQFPDFSHLCFAAETP---NSVFSDCHNYAGQDQQQDSDQDDIVCAAAENTGMPYQQGQ 130
             ...|:|       |.....||   |||                          .|:..||..|
  Rat   247 -MDLGDL-------LSLPPGTPVSGNSV--------------------------SNSLPPYLFG- 276

  Fly   131 YTQLNREDIFRFEPEDIARLTGESELPGMLQHPQTPYTPYTPYTPYTPCSAQNSQYA--VQPAND 193
                                         :::..:|| |...::...|.|.::.:.|  :.|.:|
  Rat   277 -----------------------------MENSHSPY-PSPRHSATRPHSTRSKKRALSLSPLSD 311

  Fly   194 SINLDIDYFNYDEINCQSKNQSPCSSPHLDAWLNFNLGEISAAASSSAASPKLGNVFEEQVKEEA 258
            .|.:|   ||      .....||.|   |.|::|                           ...|
  Rat   312 GIGID---FN------TIIRTSPTS---LVAYIN---------------------------GSRA 337

  Fly   259 SPAKLPSMNSTFG-----TPKCIPM-CASNYEDYANLYQQGSGYSTENYHNNMAQVVEKPNREHK 317
            |||.:...:..:|     ...|||. ||.:......|...| |::...|..
  Rat   338 SPANMSPQSEVYGHFLGVRGSCIPQSCAVSSGQKGVLVTSG-GHTLPGYGE-------------- 387

  Fly   318 AIWTIDELDELMLGEQQQFLQHHLQQQHLQEQQEQLHQP--HGQEQQTQNCKDDLVNYLSDEFIK 380
                    |..:..|:.|.|:|...|.  ......:.||  .||:.||.|            .:|
  Rat   388 --------DGTLEYERMQQLEHGGLQP--GSGNSMVLQPGLPGQDGQTAN------------MLK 430

  Fly   381 AEEFRSLDSDDDENYNEEEDDLDN--DVFAPPAESDPKP---DSTCCDPEAEPENEVIPL----- 435
            .|..        |.:.....||.:  .:..||.:..|.|   ......||..|..:.:||
  Rat   431 TERL--------EEFPASALDLPSAPPLPLPPPQGPPPPYHAHPHLHHPELLPHTQSLPLAQAGL 487

  Fly   436 -------------ICRWTGCDEEFPHQQAFVEHIEKCHVDVRKGEDFSCFWLDCPRRYKPFNARY 487
                         .|||..|...:..|:..|.||||.|:|.||||||:|||..||||||||||||
  Rat   488 EEDGELEDSGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWTGCPRRYKPFNARY 552

  Fly   488 KLLIHMRVHSGEKPNKCPFPGCNKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKH 552
            |||||||||||||||||.|.||.||||||||||||.||||||:||.||:.||.||||||||||||
  Rat   553 KLLIHMRVHSGEKPNKCTFEGCKKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKH 617

  Fly   553 QRTHYDTKPYACQLPGCTKRYTDPSSLRKHVKNHALRNANGQLRRKSAGGASV------------ 605
            ||||.||||||||:||||||||||||||||||.|:.:..  |.|:|......:
  Rat   618 QRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKEQ--QARKKLRSSTELHPDLLTDCLAVQ 680

  Fly   606 ---PPSGPKKAA-KTRRHSE-------SALV-------QRGVGAGVGVAVP-------SAPGDQR 645
               |.:.|:.|| :|..||.       ||.:       :.|..||   |||       .:||...
  Rat   681 PLQPATSPRDAADRTVGHSPGPGPELYSAPIFASNHSTRSGTAAG---AVPPPHPVSHPSPGHNV 742

  Fly   646 QHRSNSCSEAL---------------------------------LLQQHQQQQQQQQQQQ--KQH 675
            |...::.|..|                                 |||:.|....||....  |.:
  Rat   743 QGSPHNPSSHLPPLTAVDAGTERFAPPTPSPHHISPGRVPAPQSLLQRAQAPHTQQPPGSLLKPY 807

  Fly   676 QPE-------------------------NERTTDRSNCGTGVAANNNSMNFNELSNCIVIIEHNQ 715
            |||                         |...:.||     |.::::........:|:|.....|
  Rat   808 QPETNSSFQSNGIHVHGFYGQLQTFCPPNYPDSQRS-----VPSSSSCSMVPSFEDCLVPTSMGQ 867

  Fly   716 SGGPAGPATLATATATT-----TATATYGNGNMAPAPE 748
            :|.......|:|.:..|     :|:::....::...||
  Rat   868 AGFDVFHRALSTHSGITVYDLPSASSSLFGESLRSGPE 905

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lmd	NP_732811.1	SFP1	<493..585	CDD:227516	80/91 (88%)
		C2H2 Zn finger	504..526	CDD:275368	17/21 (81%)
		C2H2 Zn finger	534..556	CDD:275368	18/21 (86%)
		C2H2 Zn finger	564..586	CDD:275368	20/21 (95%)
Glis3	NP_001419411.1	C2H2 Zn finger	506..525	CDD:275368	7/18 (39%)
		C2H2 Zn finger	536..561	CDD:275368	22/24 (92%)
		COG5048	539..>839	CDD:227381	133/304 (44%)
		SFP1	<558..652	CDD:227516	81/93 (87%)
		C2H2 Zn finger	569..591	CDD:275368	17/21 (81%)
		C2H2 Zn finger	599..621	CDD:275368	18/21 (86%)
		C2H2 Zn finger	629..651	CDD:275368	20/21 (95%)