Protein Alignment lmd and glis3

DIOPT Version :9

• Sequence 1: NP_732811.1
• Gene: lmd / 42717
• FlyBaseID: FBgn0039039
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: XP_017213470.1
• Gene: glis3 / 571000
• ZFINID: ZDB-GENE-070112-2232
• Length: 804
• Species: Danio rerio
• Alignment Length: 894
• Identity: 251/894 - (28%)
• Similarity: 348/894 - (38%)
• Gaps: 229/894 - (25%)

  Fly     1 MSSSLKTSQSGGMYVKTSSISGISSISGKEAASCYGGFMSPPLSANITANNGEREMFRVPGAKVE 65
            :.:|..:.||.....:.|.:.|...:.|    ||....:....||.:.      :......|.|.
Zfish    69 LPASSSSKQSARQCCQDSGMKGYRRVFG----SCGSSNLQVSSSAFLV------QSLSPASASVT 123

  Fly    66 TNESYACGE----LQFPDFSHLCFAAETPNSVFSDCHNYAGQDQQQDSDQDDIVCAAAENTGMPY 126
            .:.|..|.:    |.|.|.|....:.|   |:.|...:.|.....:.|..|           .||
Zfish   124 HSSSQTCPQNTLTLPFNDASRCLLSRE---SLASTTLSLAETQSVRSSKLD-----------WPY 174

  Fly   127 QQGQYTQLNREDIFRFEPEDIARLTGESELPGMLQHPQTPYTPYTPY-----TPYTPCSAQNSQY 186
            .......|..:...:.....:.    ||.|...:.:|.:  .|:..:     :|.....::....
Zfish   175 GYRVLPPLGHQTANQLSESTVP----ESSLSESVSNPAS--LPHYLFKEDGSSPRLSARSKKRAL 233

  Fly   187 AVQPANDSINLDIDYFNYDEINCQSKNQSPCSSPHLDAWLNFNLGEISAAASSSAASPKLGNVFE 251
            ::.|.:|.:.||::         .....||.|   |.|::   :|...:.||.:..||...:|..
Zfish   234 SLSPLSDGLGLDLN---------SIIRTSPTS---LVAYI---IGSRISPASHNTPSPLQADVCG 283

  Fly   252 EQVKEEASPAKLPSMNSTFGTPKCIPMCASNYED-YANLY---------QQGSGYSTENYHNNMA 306
            ..:....|.....|.:| ....:.:.|  ...|| :.||.         |......|......::
Zfish   284 HLLGIRGSGIPTSSKHS-ISVSESLRM--QPLEDQFTNLLVEQQILPDPQTAKASQTHTLQFEVS 345

  Fly   307 QVVEKPNREHKAIWTIDELDELMLGEQQQFLQHHLQQQHLQEQQEQLHQPHGQEQQTQNCKDDLV 371
            ::|..|:...              |....:..||.|||  |.:..||.:|.|.:...
Zfish   346 RIVRSPSPPR--------------GPPPPYSAHHQQQQ--QPRVLQLQRPAGLQPML-------- 386

  Fly   372 NYLSDEFIKAEEFRSLDSDDDENYNEEEDDLDNDVFAPPAESDPKPDSTCCDPEAEPENEVIPLI 436
                                     |||:           |.:.....|.|
Zfish   387 -------------------------EEEE-----------EEEESCGGTHC-------------- 401

  Fly   437 CRWTGCDEEFPHQQAFVEHIEKCHVDVRKGEDFSCFWLDCPRRYKPFNARYKLLIHMRVHSGEKP 501
            |.|..|...:.|:.|.|:||||.|||.||||||:|||..|.|::|||||||||||||||||||||
Zfish   402 CCWLHCGAIYSHRDALVKHIEKIHVDQRKGEDFTCFWAGCARKHKPFNARYKLLIHMRVHSGEKP 466

  Fly   502 NKCPFPGCNKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKHQRTHYDTKPYACQL 566
            |||.|.||.||||||||||||.||||||:||.|.:.|||||||||||||||||||.||||||||:
Zfish   467 NKCSFEGCQKAFSRLENLKIHLRSHTGEKPYVCPHPGCLKAFSNSSDRAKHQRTHVDTKPYACQI 531

  Fly   567 PGCTKRYTDPSSLRKHVKNHALRNANGQLRRKSAGGASVPPSGPKKAAKTRRHSESALVQRGVGA 631
            .||.||||||||||||||:|:|:.   |..||                |.||.|:  |.|.|:
Zfish   532 QGCGKRYTDPSSLRKHVKSHSLKE---QQARK----------------KLRRSSD--LSQDGL-- 573

  Fly   632 GVGVAVPSAPGDQRQHRSNSCSEALLLQQHQQQQQQQQQ-QQKQHQPENERTTDRSNCGTGVAAN 695
                                 ||.|.:|..|........ :.|.|.|.::..|        |...
Zfish   574 ---------------------SECLTVQPLQHSLSTLDLIESKHHSPTDDLYT--------VFTL 609

  Fly   696 NNSMNFNELSNCIVIIEHNQSGGPAGPATLATATATTTA-----TATYGNGNMAPAPETEVLSVC 755
            |.....|.|::.:.|        ..||.|..:...|..|     |.|:.......|.:|:...:
Zfish   610 NQPSQTNTLNSPMQI--------AGGPQTHQSPHQTHQAHQIHQTQTHLTHQTHQAHQTQTHHI- 665

  Fly   756 SGGGSSNSNSNNNRYNANI-NQLSELEQLLTTAKPTGT-PAASANGISLANNNGRANG-DSKCHL 817
                       ...:..:: :|:.::.|  |...|.|. |....|...|:.|:.:|.| .|:...
Zfish   666 -----------QQIHQTHLTHQIQQIHQ--THLSPHGALPPLQGNNRFLSPNSHKAPGFCSQPRT 717

  Fly   818 SEFVSFEYVTKYL-TDVYEPQCKSPQPPA---NFHLQPEFDNSFD-MLD 861
            |....|..|..|. :|.:...|...|.|.   |....|:..::.. :||
Zfish   718 SAQDGFSAVFSYADSDKHISSCSVMQTPMFEDNLSSSPQIHSNISAVLD 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lmd	NP_732811.1	zf-H2C2_2	489..515	CDD:290200	22/25 (88%)
		C2H2 Zn finger	504..526	CDD:275368	17/21 (81%)
		C2H2 Zn finger	534..556	CDD:275368	18/21 (86%)
		C2H2 Zn finger	564..586	CDD:275368	18/21 (86%)
glis3	XP_017213470.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I11915
eggNOG	1	0.900	-	-		E33208_3BAZE
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26165
orthoMCL	1	0.900	-	-		OOG6_109660
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R588
SonicParanoid	1	1.000	-	-		X3347
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.790