Protein Alignment lmd and zic2

DIOPT Version :10

• Sequence 1: NP_732811.1
• Gene: lmd / 42717
• FlyBaseID: FBgn0039039
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_001017025.2
• Gene: zic2 / 549779
• XenbaseID: XB-GENE-482654
• Length: 501
• Species: Xenopus tropicalis
• Alignment Length: 333
• Identity: 110/333 - (33%)
• Similarity: 151/333 - (45%)
• Gaps: 62/333 - (18%)

  Fly   339 HHLQQQHLQEQQEQ-----LHQPHGQEQQTQNCKDDLVNYLSDEFIKAEEFRSLDSDDDENYNEE 398
            ||.|..|.:..|..     :|..|....|........:....:.|.:.|::|.:.|...:.|...
 Frog   168 HHHQLSHGEHPQGHILFPGIHDQHAAASQNALGGQMRLGLPGEMFGRTEQYRQVSSPRGDPYTAA 232

  Fly   399 EDDLDNDVFAP------------------PAESDPKPDSTCCDPEAEPENEVIPLICRW------ 439
            :  |.|. :||                  |..........|...|         |||:|
 Frog   233 Q--LHNQ-YAPMNMGMNMAAHHHHHHHHHPGAFFRYMRQQCIKQE---------LICKWIDPEQL 285

  Fly   440 ----TGCDEEFPHQQAFVEHIEKCHVDVRKGEDFSCFWLDCPRRYKPFNARYKLLIHMRVHSGEK 500
                ..|::.|......|.|:...||...:..:..|||.:|.|..|||.|:|||:.|:|||:|||
 Frog   286 SNPKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHICFWEECSREGKPFKAKYKLVNHIRVHTGEK 350

  Fly   501 PNKCPFPGCNKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKHQRTHYDTKPYACQ 565
            |..||||||.|.|:|.||||||:|:||||:|:.|:::||.:.|:|||||.||...|...|||.|:
 Frog   351 PFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCK 415

  Fly   566 LPGCTKRYTDPSSLRKHVKNHALRNANGQLRRKSAGG--ASVPPS-------------GPKKAAK 615
            :  |.|.||.|||||||:|.|.......:....::.|  :|.||.             .|..||.
 Frog   416 M--CDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPNSETQNPNLSPAAAAV 478

  Fly   616 TRRHSESA 623
            :..||.|:
 Frog   479 SAVHSVSS 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lmd	NP_732811.1	SFP1	<493..585	CDD:227516	55/91 (60%)
		C2H2 Zn finger	504..526	CDD:275368	16/21 (76%)
		C2H2 Zn finger	534..556	CDD:275368	11/21 (52%)
		C2H2 Zn finger	564..586	CDD:275368	13/21 (62%)
zic2	NP_001017025.2	zf_ZIC	269..314	CDD:436441	12/53 (23%)
		COG5048	<284..438	CDD:227381	76/155 (49%)
		C2H2 Zn finger	324..346	CDD:275368	11/21 (52%)
		C2H2 Zn finger	354..376	CDD:275368	16/21 (76%)
		C2H2 Zn finger	384..406	CDD:275368	11/21 (52%)
		C2H2 Zn finger	414..434	CDD:275368	13/21 (62%)