Protein Alignment lmd and gli1

DIOPT Version :10

• Sequence 1: NP_732811.1
• Gene: lmd / 42717
• FlyBaseID: FBgn0039039
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_840081.3
• Gene: gli1 / 352930
• ZFINID: ZDB-GENE-030321-1
• Length: 1403
• Species: Danio rerio
• Alignment Length: 913
• Identity: 230/913 - (25%)
• Similarity: 344/913 - (37%)
• Gaps: 314/913 - (34%)

  Fly     2 SSSLKTSQSGGMYVKTSSISGISSISGKEAASCYGGFMSPPLSANITANNGEREMFRVPGAKVET 66
            :||:..:.|||..|.:..:...|...|    :|...:|.||.:....:..|.|.|   |..:..:
Zfish    37 ASSVCVALSGGQSVNSREMYNPSMAPG----ACMEPYMRPPHAPPPHSMMGHRGM---PPPEGMS 94

  Fly    67 NESYACGELQFPDFSHLCFAAETPNSVFSDCHNYAGQDQQQDSDQDDIVCAAAENTGMPYQQGQY 131
            ...| |.:                 ::.:..||                        :|:.|...
Zfish    95 GAPY-CNQ-----------------NMMTSHHN------------------------LPHNQHTS 117

  Fly   132 TQLNREDIFRFE-PEDIARLTGESELPGMLQHPQTPYTPYTPYTPYTPCSAQNSQYAVQPANDSI 195
            ..:...|...|. |..:.:|:.:..|               ..:|.:..|. :.|..::.:.:|:
Zfish   118 ELMASGDASCFSTPRSMLKLSKKRAL---------------SISPLSDASV-DLQTVIRTSPNSL 166

  Fly   196 NLDIDYFNYDEINCQSKNQSPCSSPHLDAWLNFNLGEISAA---ASSSAASPKLGNVFEEQVKE- 256
               :.:.|   ..|...|  |.|..||      ::|.:|.:   :||...|...||::...|..
Zfish   167 ---VAFVN---SRCGPNN--PSSYGHL------SVGTMSPSLGFSSSINYSRPQGNIYSHPVPSC 217

  Fly   257 EASPAKLPSMNSTFGTPKCIPMCASNYEDYANLYQQGSGYSTENYHNNMAQVVEKPNREHKAIWT 321
            ..:||:||..|....||                                        .:|..:.|
Zfish   218 IGAPARLPPHNPRLHTP----------------------------------------AKHTHLKT 242

  Fly   322 IDELDELMLGEQQQFLQHHLQQQHLQEQQEQLHQPHGQEQQTQNCKDDLVNYLSDEFIKAEEFRS 386
            ...|..:|.....:.|:.|        .:..:..|     .:...:|.|:..|
Zfish   243 EPVLGSVMDSINIKGLEDH--------SEGDVASP-----SSTGTQDPLLGLL------------ 282

  Fly   387 LDSDDDENYNEEEDDLDNDVFAPPAESDPKPDSTCCDPEAEPENEVIPLICRWTGCDEEFPHQQA 451
                      |..||||         .:.||     :|||..|..     |.|..|.:||..|:.
Zfish   283 ----------EGRDDLD---------KEEKP-----EPEAIYETN-----CHWESCSKEFDTQEQ 318

  Fly   452 FVEHIEKCHVDVRKGEDFSCFWLDCPRRYKPFNARYKLLIHMRVHSGEKPNKCPFPGCNKAFSRL 516
            .|.||...|:...| ::|.|.|.||.|..:||.|:|.|::|||.|:||||:||.|.|||||:|||
Zfish   319 LVHHINNEHIHGEK-KEFVCHWKDCSREQRPFKAQYMLVVHMRRHTGEKPHKCTFEGCNKAYSRL 382

  Fly   517 ENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKHQ-RTHYDTKPYACQLPGCTKRYTDPSSLR 580
            ||||.|.||||||:||.|:::||.|||||:||||||| |||.:.|||.|::||||||||||||||
Zfish   383 ENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLR 447

  Fly   581 KHVKN-HALRNANGQLRRKSAGGASVPPSGPKKAAKTRRHSESALVQRGVGAGVGVAVPSAPGDQ 644
            ||||. |                      || :|..|::|.             |...|..||..
Zfish   448 KHVKTVH----------------------GP-EAHITKKHR-------------GDTGPRPPGLT 476

  Fly   645 RQHRSNSCSEALLLQQHQQQQQQQQQQQKQHQPENERTTD-----RSNCGT-----GVAANNNS- 698
            ...:|   ||.|:     :::::.::..|...|:|...:.     :|:|.:     |.|.||:|
Zfish   477 TAGQS---SELLI-----EKEERNREDCKLLAPDNTLKSQPSPGGQSSCSSERSPLGSANNNDSG 533

  Fly   699 --MNFNELSNCIVIIEHNQSGGPAGPATLATATATTTATATYGNGNMAPAPETEVLSVCSGGGSS 761
              ||.|...:    :|...:...:|.|.::.::||                      |.|||...
Zfish   534 VEMNLNAAGS----LEDLTTQEDSGNAGVSESSAT----------------------VSSGGMCM 572

  Fly   762 NSNSNNNRYNANINQLSELEQLLTTAKPTGT--PAASA--------------------------- 797
            :..:.....|..|::|.::.:.....:..|.  ||.||
Zfish   573 SVQALKRLENLKIDKLKQIRRPTPPGRNAGNKLPALSATGEMMSMCAPSPLLSNRRVMELSAPDM 637

  Fly   798 ---NGISLANNNGRANGDSKCHLSEFVS--FEYVTKYL-----TDVYEPQCKS---------PQP 843
               .|:|...|:.|.:|.|....:..||  ...|:.||     :||  ..|:|         |..
Zfish   638 GGVTGMSCPPNDRRGSGTSSLSSAYTVSRRSSMVSPYLSSRRSSDV--SHCQSVMGGEVPGDPLS 700

  Fly   844 PAN 846
            |.|
Zfish   701 PQN 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lmd	NP_732811.1	SFP1	<493..585	CDD:227516	70/92 (76%)
		C2H2 Zn finger	504..526	CDD:275368	16/21 (76%)
		C2H2 Zn finger	534..556	CDD:275368	16/22 (73%)
		C2H2 Zn finger	564..586	CDD:275368	19/22 (86%)
gli1	NP_840081.3	None