Protein Alignment lmd and Glis1

DIOPT Version :9

• Sequence 1: NP_732811.1
• Gene: lmd / 42717
• FlyBaseID: FBgn0039039
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: XP_006238623.1
• Gene: Glis1 / 298732
• RGDID: 1308030
• Length: 793
• Species: Rattus norvegicus
• Alignment Length: 517
• Identity: 186/517 - (35%)
• Similarity: 240/517 - (46%)
• Gaps: 141/517 - (27%)

  Fly   397 EEEDDLDNDVFAPPAESDPKPDSTCCDPEAEPENEVIPLI-----------------CRWTGCDE 444
            :|..|..:::|||..:..|.|...       |:....|.:                 |||..|..
  Rat   322 QEPMDEFSELFAPHQQGLPPPYPL-------PQLPTGPSLGGLGLGLAGRMAAGRQACRWVDCCA 379

  Fly   445 EFPHQQAFVEHIEKCHVDVRKGEDFSCFWLDCPRRYKPFNARYKLLIHMRVHSGEKPNKCPFPGC 509
            .:..|:..|.||||.|:|.||||||:|||..|.|||||||||||||||||||||||||||.|.||
  Rat   380 AYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGC 444

  Fly   510 NKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKHQRTHYDTKPYACQLPGCTKRYT 574
            :||||||||||||.||||||:||.||:.||.||||||||||||||||.||||||||:|||:||||
  Rat   445 SKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYT 509

  Fly   575 DPSSLRKHVKNHALRNANGQLRRKSAGGASVPPSGPKKAAKTRRHSESALVQRGVGAGVGVAVPS 639
            ||||||||||.|:.:..  |:|:|...||.               .|:|::
  Rat   510 DPSSLRKHVKAHSAKEQ--QVRKKLHTGAD---------------PEAAVL-------------- 543

  Fly   640 APGDQRQHRSNSCSEALLLQQHQQQQQQQQQQQKQHQPENER---------TTDRSNCGTGVAAN 695
                         ||.|.|||.|........:.|..|..::.         .|.::...:|:.:.
  Rat   544 -------------SECLALQQLQASTPLPASRGKGSQTLSQELLPGVYPGSVTPQNGLASGILSP 595

  Fly   696 NNSM------------NFNELSNCIVIIEHNQSG-GPA------------GPATLATAT------ 729
            ::.:            :.:.||. :...|..:.| ||.            ||..|..|:
  Rat   596 SHDVPSRHHPLEVTTGSHHHLSP-LPTAESTRDGLGPGLLSPMVSPLKGLGPPPLPPASQSQSPG 659

  Fly   730 ----ATTTATATYGNGNMAPAPETEVLSVCSGGGSSNSNSNNNRYNANINQLSELEQLLTTAKPT 790
                :|..:..||......|.|   :.|.....||.:|..|...| |:..:.:|
  Rat   660 AQSFSTIPSKPTYPPFQSPPPP---LPSPQGYQGSFHSIQNCFPY-ADCYRTTE----------- 709

  Fly   791 GTPAASANGISLANNNGRANGDSKCHLSEFVSFEYVTKYLTDVYEPQCKSPQPPANFHLQPE 852
              ||||.:|:.     |.|:|.:....|.:.|..  |......||...::|.|.    |||:
  Rat   710 --PAASRDGLV-----GDAHGFNPLRPSTYSSLS--TPLSAPGYEALAETPCPT----LQPQ 758

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lmd	NP_732811.1	zf-H2C2_2	489..515	CDD:290200	22/25 (88%)
		C2H2 Zn finger	504..526	CDD:275368	17/21 (81%)
		C2H2 Zn finger	534..556	CDD:275368	18/21 (86%)
		C2H2 Zn finger	564..586	CDD:275368	19/21 (90%)
Glis1	XP_006238623.1	C2H2 Zn finger	376..395	CDD:275368	7/18 (39%)
		C2H2 Zn finger	406..431	CDD:275368	21/24 (88%)
		COG5048	435..>514	CDD:227381	66/78 (85%)
		C2H2 Zn finger	439..461	CDD:275368	17/21 (81%)
		zf-H2C2_2	453..480	CDD:290200	20/26 (77%)
		C2H2 Zn finger	469..491	CDD:275368	18/21 (86%)
		C2H2 Zn finger	499..521	CDD:275368	19/21 (90%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	67	1.000	Domainoid score	I9566
eggNOG	1	0.900	-	-		E33208_3BAZE
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006952
OrthoInspector	1	1.000	-	-		otm45031
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3347
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.860