Protein Alignment lmd and Sp4

DIOPT Version :10

• Sequence 1: NP_732811.1
• Gene: lmd / 42717
• FlyBaseID: FBgn0039039
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_036893.1
• Gene: Sp4 / 25162
• RGDID: 3741
• Length: 783
• Species: Rattus norvegicus
• Alignment Length: 751
• Identity: 144/751 - (19%)
• Similarity: 233/751 - (31%)
• Gaps: 252/751 - (33%)

  Fly     5 LKTSQSGG----MYVKTSSISGISSISGKEAASCYGGFMSPPLSANITANNGEREMFRVPGAKVE 65
            |.|:|..|    :...|...|..:::|...::|          |::.::|||.....:.......
  Rat    90 LVTTQLAGNAWQLVASTPPASKENNVSQPASSS----------SSSSSSNNGSSSPTKTKSGNPS 144

  Fly    66 TNESYACGELQFPDFSHLCFAAETPNSVFSDCHNYAGQDQQ---------QDSDQDDIVCAAAEN 121
            |...:...::|.|       :......|........||..|         ||. |..|...:|.|
  Rat   145 TPNQFQVIQVQNP-------SGSVQYQVIPQLQTVEGQQIQINPTSSSSLQDL-QGQIQLISAGN 201

  Fly   122 TGMPYQQGQYTQLNREDIFRFEPEDIARLTGESEL-PGM---LQHPQTPYT--------PYT--- 171
                 .|...|..||........:::|..|...:: ||:   ||....|.|        |..
  Rat   202 -----NQAILTAANRTASGNILAQNLANQTVPVQIRPGVSIPLQLQTLPGTQAQVVTTLPINIGG 261

  Fly   172 ----------------------PYTPYTPCSAQNSQYAVQPANDSINLDIDYFNYDEINCQSKNQ 214
                                  |.|..|.....|....|.....|           .....:..:
  Rat   262 VTLALPVINNVTAGGGTGQVGQPTTTTTDSGTSNGNQLVSTPTTS-----------TAPASTMPE 315

  Fly   215 SPCSSPHLDAWLNFNLGE----ISAA-----ASSSAASPKLGNVFEEQVKEEASPAKLPSMNSTF 270
            ||.||.......:.:|..    :|:|     ||:||:|.      |..::|..:||
  Rat   316 SPSSSTTCTTTASTSLTSSDTLVSSADTGQYASTSASSS------ERTIEEPQTPA--------- 365

  Fly   271 GTPKCIPMCASNYEDYANLYQQGSGYSTENYHNN---MAQVVEKPNREHKAIWTIDELDELMLGE 332
                     |:..|..::...|.:|.......:|   ..|:|.:|           .|.::.:.:
  Rat   366 ---------ATESEAQSSSQLQSNGIQNAQDQSNSLQQVQIVGQP-----------ILQQIQIQQ 410

  Fly   333 QQQFLQHHLQQQHLQEQQEQLHQPHGQEQQTQNCKDDLVN---------------YLSDEFIKAE 382
            .||.:...:..|..|.|..|..|.. |:|..||.:...||               .:|.:.::.:
  Rat   411 PQQQIIQAIPPQSFQLQSGQTIQTI-QQQPLQNVQLQAVNPTQVLIRAPTLTPSGQISWQTVQVQ 474

  Fly   383 EFRSLDSDDDENYNEEEDDLDNDVFAPPAESDP-------KPDSTCCDP---------------- 424
            ..:||     .|...:...|...:...|..|..       .|.:....|
  Rat   475 NIQSL-----SNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVAVAGAPITLNTAQLASVPNLQT 534

  Fly   425 -------EAEPENEVIPLICRWTGCDEE----FPHQQAFV--------------------EHIEK 458
                   .|..:.:.:|:........::    ...|||.:                    :.:.:
  Rat   535 VSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANATIGAVSPDQLTQ 599

  Fly   459 CHV---------DVRKGEDFSCFWLDCPRRYKPFNARYKLLIHMRVHSGE-----KPNK-----C 504
            .|:         :|:.|:........||      |.|          .||     :|.|     |
  Rat   600 VHLQQGQQTSDAEVQPGKRLRRVACSCP------NCR----------EGEGRGSSEPGKKKQHVC 648

  Fly   505 PFPGCNKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKHQRTHYDTKPYACQLPGC 569
            ...||.|.:.:..:|:.|.|.||||||:.|.:..|.|.|:.|.:..:|:|||...|.:.|  |.|
  Rat   649 HIEGCGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKRFEC--PEC 711

  Fly   570 TKRYTDPSSLRKHVKNHALRNANGQLRRKSAGGASV 605
            :||:.....|.||||.|         :.|..||.::
  Rat   712 SKRFMRSDHLSKHVKTH---------QNKKGGGTAL 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lmd	NP_732811.1	SFP1	<493..585	CDD:227516	36/101 (36%)
		C2H2 Zn finger	504..526	CDD:275368	7/21 (33%)
		C2H2 Zn finger	534..556	CDD:275368	7/21 (33%)
		C2H2 Zn finger	564..586	CDD:275368	10/21 (48%)
Sp4	NP_036893.1	SP4_N	30..647	CDD:411773	107/647 (17%)
		zf-C2H2	646..670	CDD:395048	7/23 (30%)
		C2H2 Zn finger	648..670	CDD:275368	7/21 (33%)
		zf-C2H2	676..700	CDD:395048	7/23 (30%)
		C2H2 Zn finger	678..700	CDD:275368	7/21 (33%)
		zf-H2C2_2	692..715	CDD:463886	9/24 (38%)
		zf-C2H2	706..728	CDD:395048	10/23 (43%)
		C2H2 Zn finger	708..728	CDD:275368	10/21 (48%)