Protein Alignment lmd and Glis1

DIOPT Version :9

• Sequence 1: NP_732811.1
• Gene: lmd / 42717
• FlyBaseID: FBgn0039039
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: XP_006503035.1
• Gene: Glis1 / 230587
• MGIID: 2386723
• Length: 804
• Species: Mus musculus
• Alignment Length: 534
• Identity: 193/534 - (36%)
• Similarity: 244/534 - (45%)
• Gaps: 142/534 - (26%)

  Fly   402 LDNDVFAPPAESDPKPDST----------CC--------DPEAE------PENEVIP-------- 434
            |..|:..||..|.|.|.|:          .|        :|..|      |.::.:|
Mouse   295 LPGDLGGPPKRSRPGPASSDGQEGSLQLEACRKSGFLKQEPMDEFSELFAPHHQGLPPPYPLPQL 359

  Fly   435 ---------------------LICRWTGCDEEFPHQQAFVEHIEKCHVDVRKGEDFSCFWLDCPR 478
                                 ..|||..|...:..|:..|.||||.|:|.||||||:|||..|.|
Mouse   360 PTGPGLGGLGLGLAGRMVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVR 424

  Fly   479 RYKPFNARYKLLIHMRVHSGEKPNKCPFPGCNKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAF 543
            ||||||||||||||||||||||||||.|.||:||||||||||||.||||||:||.||:.||.|||
Mouse   425 RYKPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAF 489

  Fly   544 SNSSDRAKHQRTHYDTKPYACQLPGCTKRYTDPSSLRKHVKNHALRNANGQLRRKSAGGASVPPS 608
            |||||||||||||.||||||||:|||:||||||||||||||.|:.:..  |:|:|...||.....
Mouse   490 SNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQ--QVRKKLHTGADPEAD 552

  Fly   609 GPKKAAKTRRHSESALV--QRGVGA---------GV--GVAVPSAPGDQRQHRSNSCSEALLLQQ 660
            ...:....::...|.|:  .||.|:         ||  |...|          .|..:..:|...
Mouse   553 VLSECLSLQQLQASTLLPASRGKGSQTLSQELLPGVYPGSVTP----------QNGLASGILSPS 607

  Fly   661 HQQQQQQQQQQ---QKQHQ----PENERTTDRSNCGTGVAANNNSMNFNELSNCIVIIE------ 712
            |....:....:   ...|.    |..|.|.|    |.|.:.         ||..:..::
Mouse   608 HDVPSRHHPLEVPTGSHHHLSPLPTAESTRD----GLGPSL---------LSPMVSPLKGLGPPP 659

  Fly   713 ---HNQSGGPAGPATLATATATTTATATYGN-GNMAPAPETEVLSVCSGGGSSNSNSNNNRYNAN 773
               .:||..|.|     .:.:|..:..||.: .:..|.|..:...     ||.:|..|...| |:
Mouse   660 LPPASQSQSPGG-----QSFSTVPSKPTYPSFQSPPPLPSPQGYQ-----GSFHSIQNCFPY-AD 713

  Fly   774 INQLSELEQLLTTAKPTGTPAASANGISLANNNGRANGDSKCHLSEFVSFEYVTKYLTDVYEPQC 838
            ..:.:|             ||||.:|:.     |.|:|.:....|.:.|..  |......||...
Mouse   714 CYRATE-------------PAASRDGLV-----GDAHGFNPLRPSTYSSLS--TPLSAPGYETLA 758

  Fly   839 KSPQPPANFHLQPE 852
            ::|.|||   |||:
Mouse   759 ETPCPPA---LQPQ 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lmd	NP_732811.1	zf-H2C2_2	489..515	CDD:290200	22/25 (88%)
		C2H2 Zn finger	504..526	CDD:275368	17/21 (81%)
		C2H2 Zn finger	534..556	CDD:275368	18/21 (86%)
		C2H2 Zn finger	564..586	CDD:275368	19/21 (90%)
Glis1	XP_006503035.1	C2H2 Zn finger	387..406	CDD:275368	7/18 (39%)
		C2H2 Zn finger	417..442	CDD:275368	21/24 (88%)
		COG5048	446..>525	CDD:227381	66/78 (85%)
		C2H2 Zn finger	450..472	CDD:275368	17/21 (81%)
		C2H2 Zn finger	480..502	CDD:275368	18/21 (86%)
		C2H2 Zn finger	510..532	CDD:275368	19/21 (90%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	67	1.000	Domainoid score	I9777
eggNOG	1	0.900	-	-		E33208_3BAZE
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006952
OrthoInspector	1	1.000	-	-		otm42966
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3347
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.860