Protein Alignment lmd and Zic3

DIOPT Version :10

• Sequence 1: NP_732811.1
• Gene: lmd / 42717
• FlyBaseID: FBgn0039039
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_033601.2
• Gene: Zic3 / 22773
• MGIID: 106676
• Length: 466
• Species: Mus musculus
• Alignment Length: 455
• Identity: 136/455 - (29%)
• Similarity: 199/455 - (43%)
• Gaps: 117/455 - (25%)

  Fly   234 SAAASSSAASPKLGNVFEEQVKEEASPA---KLPSMNSTFGTPKCIPMCASNYEDYANLYQQGSG 295
            :|||:::||:.||            |||   .|.|..|:..||                  ||||
Mouse    46 AAAAAAAAAAFKL------------SPATAHDLSSGQSSAFTP------------------QGSG 80

  Fly   296 YST-------ENYHNNMAQVVEKPNREHKAIWTIDELDELMLGEQQQFL--------QHHLQQQH 345
            |:.       .::|::.:||   |.....|....:...:.:..::...|        ||.|
Mouse    81 YANALGHHHHHHHHHHASQV---PTYGGAASAAFNSTRDFLFRQRGSGLSEAASGGGQHGL---- 138

  Fly   346 LQEQQEQLHQPHG-------------QEQ------QTQNCKDDLVNY-LSDE-FIKAEEFRSLDS 389
            .......||.|.|             .||      .|.:..::.|:. |..| |.:|:.:|.:.|
Mouse   139 FAGSASSLHAPAGIPEPPSYLLFPGLHEQGAGHPSPTGHVDNNQVHLGLRGELFGRADPYRPVAS 203

  Fly   390 DDDE---------NYNEEEDDLDNDVFAPPAESDPKPDSTCCDPEA------EPENEVIPLICRW 439
            ...:         ||:....::..:|.|...            |.|      :|..:  .|.|:|
Mouse   204 PRTDPYAASAQFPNYSPMNMNMGVNVAAHHG------------PGAFFRYMRQPIKQ--ELSCKW 254

  Fly   440 ----------TGCDEEFPHQQAFVEHIEKCHVDVRKGEDFSCFWLDCPRRYKPFNARYKLLIHMR 494
                      ..||..|......|.|:...||...:..:..|:|.:|||..|.|.|:|||:.|:|
Mouse   255 IEEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIR 319

  Fly   495 VHSGEKPNKCPFPGCNKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKHQRTHYDT 559
            ||:||||..||||||.|.|:|.||||||:|:||||:|:.|:::||.:.|:|||||.||...|...
Mouse   320 VHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSD 384

  Fly   560 KPYACQLPGCTKRYTDPSSLRKHVKNHALRNANGQLRRKSAGGASVPPSGPKKAAKTRRHSESAL 624
            |||.|::  |.|.||.|||||||:|.|..:.::......|...:|.||:.....:|....:.||:
Mouse   385 KPYICKV--CDKSYTHPSSLRKHMKVHESQGSDSSPAASSGYESSTPPAIASANSKDTTKTPSAV 447

  Fly   625  624
            Mouse   448  447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lmd	NP_732811.1	SFP1	<493..585	CDD:227516	55/91 (60%)
		C2H2 Zn finger	504..526	CDD:275368	16/21 (76%)
		C2H2 Zn finger	534..556	CDD:275368	11/21 (52%)
		C2H2 Zn finger	564..586	CDD:275368	13/21 (62%)
Zic3	NP_033601.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..103		14/58 (24%)
		zf_ZIC	244..289	CDD:436441	11/46 (24%)
		Nuclear localization signal. /evidence=ECO:0000250	296..321		13/24 (54%)
		C2H2 Zn finger	301..321	CDD:275368	11/19 (58%)
		SFP1	<323..407	CDD:227516	52/85 (61%)
		C2H2 Zn finger	329..351	CDD:275368	16/21 (76%)
		Nuclear localization signal. /evidence=ECO:0000250	329..351		16/21 (76%)
		C2H2 Zn finger	359..381	CDD:275368	11/21 (52%)
		C2H2 Zn finger	389..409	CDD:275368	13/21 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	403..466		12/45 (27%)