Protein Alignment lmd and Glis3

DIOPT Version :10

• Sequence 1: NP_732811.1
• Gene: lmd / 42717
• FlyBaseID: FBgn0039039
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_780668.3
• Gene: Glis3 / 226075
• MGIID: 2444289
• Length: 935
• Species: Mus musculus
• Alignment Length: 721
• Identity: 228/721 - (31%)
• Similarity: 288/721 - (39%)
• Gaps: 220/721 - (30%)

  Fly    15 VKTSS------ISGISSISGKEAASCYGGFMSPPLSANITANNGER------------------- 54
            |.|||      :..||..:.:.:.:|..  :||.|...:.|.|..|
Mouse   150 VVTSSPMMVQRLGPISPPASQVSTACKQ--ISPSLPRAVNAANLNRPPSDTRSVILQESLVSTTL 212

  Fly    55 ---EMFRVPGAKVETNESYACGELQFPDFSHLCFAAETPNSVFSDCHNYAGQDQQQDSDQDDIVC 116
               |.......|.|.::||..    ||..|                   :....|..:|..|::.
Mouse   213 SLTESQSALSVKQEWSQSYRA----FPSLS-------------------SSHSSQNGTDLGDLLS 254

  Fly   117 AAAENTGMPYQQGQYTQLNREDIFRFEPEDIARLTGES---ELPGMLQHPQTPYTPY-TPYTPYT 177
            ..   .|.|                        ::|.|   .||..|...:..::|| :|....|
Mouse   255 LP---PGTP------------------------VSGNSVSNSLPPYLFGMENSHSPYPSPRHSAT 292

  Fly   178 PCSAQNSQ---YAVQPANDSINLDIDYFNYDEINCQSKNQSPCSSPHLDAWLNFNLGEISAAASS 239
            ...:..|:   .::.|.:|.|.:|   ||      .....||.|   |.|::|
Mouse   293 RAHSTRSKKRALSLSPLSDGIGID---FN------TIIRTSPTS---LVAYIN------------ 333

  Fly   240 SAASPKLGNVFEEQVKEEASPAKLPSMNSTFG-----TPKCIPMCASNYEDYANLYQQGSGYSTE 299
               .|:            ||||.|...:..:|     ...|||...:.......:.....|::..
Mouse   334 ---GPR------------ASPANLSPQSEVYGHFLGVRGSCIPQSCAVASGQKGILVASGGHTLP 383

  Fly   300 NYHNNMAQVVEKPNREHKAIWTIDELDELMLGEQQQFLQH-HLQQQHLQEQQEQLHQPHGQEQQT 363
            .|..                      |..:..|:.|.|:| .||...:.....|...| ||:.||
Mouse   384 GYGE----------------------DGTLEYERMQQLEHGGLQPGPVNNMVLQPGLP-GQDGQT 425

  Fly   364 QNCKDDLVNYLSDEFIKAEEFRSLDSDDDENYNEEEDDLDN--DVFAPPAESDPKP---DSTCCD 423
            .|            .:|.|..        |.:.....||.:  .:..||.:..|.|   ......
Mouse   426 AN------------MLKTERL--------EEFPASALDLPSALPLPLPPPQGPPPPYHAHPHLHH 470

  Fly   424 PEAEPENEVIPL------------------ICRWTGCDEEFPHQQAFVEHIEKCHVDVRKGEDFS 470
            ||..|..:.:.|                  .|||..|...:..|:..|.||||.|:|.||||||:
Mouse   471 PELLPHTQSLSLAQTGLEEDGEMEDSGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFT 535

  Fly   471 CFWLDCPRRYKPFNARYKLLIHMRVHSGEKPNKCPFPGCNKAFSRLENLKIHQRSHTGERPYGCQ 535
            |||..|||||||||||||||||||||||||||||.|.||.||||||||||||.||||||:||.||
Mouse   536 CFWTGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCKKAFSRLENLKIHLRSHTGEKPYLCQ 600

  Fly   536 YKGCLKAFSNSSDRAKHQRTHYDTKPYACQLPGCTKRYTDPSSLRKHVKNHALRNANGQLRRKSA 600
            :.||.||||||||||||||||.||||||||:||||||||||||||||||.|:.|..  |.|:|..
Mouse   601 HPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSREQ--QARKKLR 663

  Fly   601 GGASV---------------PPSGPKKAA-KTRRHSESALVQRGVGAGVGVAVPSAPGDQRQHRS 649
            ....:               |.:.|..|| .|..||...    |.|.|.|..:.|||.....|.:
Mouse   664 SSTELHPDLLTDCLAVQPLQPATSPGDAADHTVGHSPGP----GPGPGPGAELYSAPIFASNHST 724

  Fly   650 NSCSEA 655
            .|.:.|
Mouse   725 RSGTAA 730

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lmd	NP_732811.1	SFP1	<493..585	CDD:227516	80/91 (88%)
		C2H2 Zn finger	504..526	CDD:275368	17/21 (81%)
		C2H2 Zn finger	534..556	CDD:275368	18/21 (86%)
		C2H2 Zn finger	564..586	CDD:275368	20/21 (95%)
Glis3	NP_780668.3	C2H2 Zn finger	506..525	CDD:275368	7/18 (39%)
		C2H2 Zn finger	536..561	CDD:275368	22/24 (92%)
		SFP1	<558..652	CDD:227516	81/93 (87%)
		C2H2 Zn finger	569..591	CDD:275368	17/21 (81%)
		C2H2 Zn finger	599..621	CDD:275368	18/21 (86%)
		PHA03247	<612..861	CDD:223021	58/125 (46%)
		C2H2 Zn finger	629..651	CDD:275368	20/21 (95%)