DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment lmd and Mtf1

DIOPT Version :9

Sequence 1:NP_732811.1 Gene:lmd / 42717 FlyBaseID:FBgn0039039 Length:866 Species:Drosophila melanogaster
Sequence 2:NP_032662.3 Gene:Mtf1 / 17764 MGIID:101786 Length:675 Species:Mus musculus


Alignment Length:649 Identity:144/649 - (22%)
Similarity:203/649 - (31%) Gaps:279/649 - (42%)


- Green bases have known domain annotations that are detailed below.


  Fly   392 DEN---YNEEEDDL----------DNDVFAPPA------------ESDP------KPDSTCCDP- 424
            |:|   :..|||||          |::...|.:            |.||      :.|..|.:| 
Mouse     7 DDNIIFFKGEEDDLTPHDKMLRFVDDNGLVPSSSGTVYDRTTVLIEQDPGTLEDDEDDGQCGEPL 71

  Fly   425 ----EAEPENEVIPLICRWTGCDEEFPHQQAFVEHI---EKCHVDVRKG---------------- 466
                |.| |..:|         |:| ...|.:|:||   ::.|:.:..|                
Mouse    72 PFLVEGE-EGFLI---------DQE-AMSQGYVQHIISPDQIHLTINPGSTPMPRNIEGATLTLQ 125

  Fly   467 -----------EDFSCFWLDCPRRY---------------------------KPFNARYKLLIHM 493
                       :.:.|.:..|||.|                           |.|...|.|.||:
Mouse   126 SECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHV 190

  Fly   494 RVHSGEKPNKCPFPGCNKAFSRLENLKIHQ-----------------------------RSHTGE 529
            |||:.|||.:|...||.|||:.|..||.||                             |:||||
Mouse   191 RVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESQGCSKYFTTLSDLRKHIRTHTGE 255

  Fly   530 RPYGCQYKGCLKAFSNSSDRAKHQRTHYDTKPYACQLPGCTKRYTDPSSLRKHVKNH-------- 586
            :|:.|.:.||.|||:.|.....|.|||...:|:.|...||.|.::...||:.|:|.|        
Mouse   256 KPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGHDNKGTAYS 320

  Fly   587 ALRNANG--------------------QLRRKSA------------------------------- 600
            ||...||                    :|:..|:                               
Mouse   321 ALPQHNGSEDTNHSLYLSELGLLSTDSELQENSSSTQDQDLSTISPAIIFESMFQNSDDPGIQDD 385

  Fly   601 ------------GGASVPPSGPKKAAKTRRHSESALVQRGVGAG----VGVAVPSAP------GD 643
                        |.|......|..|..:...|...::|.|:...    :....||||      |.
Mouse   386 PLQTAALIDSFNGDAESVIDVPPPAGNSASLSLPLVLQSGISEPPQPLLPATAPSAPPPAPSLGP 450

  Fly   644 QRQHRSNSCSEALLLQQHQQQQQQQQQQQKQHQ---PENERTTDRSNCGTGVAANNNSMNFNELS 705
            ..|..:.. |...|||..:.......|....||   |..:........|..|.|           
Mouse   451 GSQPAAFG-SPPALLQPPEVPVPHSTQFAANHQEFLPHPQAPPQTIVPGLSVVA----------- 503

  Fly   706 NCIVIIEHNQSGGPAGPATLATATA------TTT-------------ATATYGNG---NMAPAPE 748
                       |.||..||:|:|.|      :||             |.:...|.   .:.|.|.
Mouse   504 -----------GAPASAATVASAVAAPAPPQSTTEPLPAMVQTLPLGANSVLTNNPTITITPTPN 557

  Fly   749 TEVL--SVCSG--------GGSSNSNSNNNRYNANINQLSELEQLLTTAKPTGTPAASANGISL 802
            |.:|  |:..|        .|:::|..|..:    |.|.|::||:...   |..|.||..|.|:
Mouse   558 TAILQSSLVMGEQNLQWILNGATSSPQNQEQ----IQQASKVEQVYFA---TAVPVASGTGSSV 614

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
lmdNP_732811.1 zf-H2C2_2 489..515 CDD:290200 15/25 (60%)
C2H2 Zn finger 504..526 CDD:275368 12/50 (24%)
C2H2 Zn finger 534..556 CDD:275368 9/21 (43%)
C2H2 Zn finger 564..586 CDD:275368 8/21 (38%)
Mtf1NP_032662.3 COG5048 <92..308 CDD:227381 57/215 (27%)
Nuclear localization signal. /evidence=ECO:0000255 132..137 0/4 (0%)
C2H2 Zn finger 141..163 CDD:275368 5/21 (24%)
zf-H2C2_2 155..182 CDD:290200 2/26 (8%)
C2H2 Zn finger 171..193 CDD:275368 7/21 (33%)
zf-H2C2_2 185..212 CDD:290200 15/26 (58%)
C2H2 Zn finger 201..223 CDD:275368 11/21 (52%)
C2H2 Zn finger 235..252 CDD:275368 1/16 (6%)
zf-H2C2_2 244..270 CDD:290200 11/25 (44%)
C2H2 Zn finger 260..282 CDD:275368 9/21 (43%)
zf-H2C2_2 274..301 CDD:290200 9/26 (35%)
C2H2 Zn finger 290..312 CDD:275368 8/21 (38%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 427..464 7/37 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 645..675
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR19818
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

Return to query results.
Submit another query.