Protein Alignment lmd and KLF12

DIOPT Version :10

• Sequence 1: NP_732811.1
• Gene: lmd / 42717
• FlyBaseID: FBgn0039039
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: XP_011533209.1
• Gene: KLF12 / 11278
• HGNCID: 6346
• Length: 415
• Species: Homo sapiens
• Alignment Length: 424
• Identity: 87/424 - (20%)
• Similarity: 159/424 - (37%)
• Gaps: 110/424 - (25%)

  Fly   189 QPANDSINLDIDYFNYD----EINCQSKNQSPCSSPHLDAWLNFNLGEISAAASSSAASPKLGNV 249
            :|..||  |.:|:|...    :::......||.:.......:..:....|:.::||::|.:|.
Human    77 EPPEDS--LSVDHFQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLA-- 137

  Fly   250 FEEQVKEEASPAKLPSM-----NSTFGTPKCIPMCASNY--EDYANLYQQGSGYSTENYHNNMAQ 307
                    :||..:.|:     :||..||..:...||..  :.:.::.......|..|..:|
Human   138 --------SSPTVITSVSSASSSSTVLTPGPLVASASGVGGQQFLHIIHPVPPSSPMNLQSN--- 191

  Fly   308 VVEKPNREHKAIWTIDELDELMLGEQQQFLQHHLQQQHLQEQQEQLHQPHGQEQQTQNCKDDLVN 372
               |.:..|:....:..:..:....:.....::.....|.|.    .:.||:.|
Human   192 ---KLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLED----GRGHGKAQ----------- 238

  Fly   373 YLSDEFIKAEEFRSLDSDDDENYNEEEDDLDN------DVFAPPAESDPKPDSTCCDPEAEPENE 431
             :....:...:.:| |||||:..|...|.::.      .:.....|..|.|
Human   239 -MDPRGLSPRQSKS-DSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSP-------------- 287

  Fly   432 VIPLICRWTG---CDEEFPHQQAFVEHIEKCHVDVRKGEDFSCFWLDCPRRYK----PFNARYKL 489
                :.|..|   .:::||           |.:        |.|.::..||.:    |.:.:
Human   288 ----VSRVRGNRMNNQKFP-----------CSI--------SPFSIESTRRQRRSESPDSRK--- 326

  Fly   490 LIHMRVHSGEKPNKCPFPGCNKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKHQR 554
               .|:|      :|.|.||||.:::..:||.|:|:||||:||.|.::||...|:.|.:..:|.|
Human   327 ---RRIH------RCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYR 382

  Fly   555 THYDTKPYACQLPGCTKRYTDPSSLRKHVKNHAL 588
            .|...||:.|  ..|.:.::....|..|.:.|.|
Human   383 KHTGVKPFKC--ADCDRSFSRSDHLALHRRRHML 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lmd	NP_732811.1	SFP1	<493..585	CDD:227516	32/91 (35%)
		C2H2 Zn finger	504..526	CDD:275368	10/21 (48%)
		C2H2 Zn finger	534..556	CDD:275368	7/21 (33%)
		C2H2 Zn finger	564..586	CDD:275368	4/21 (19%)
KLF12	XP_011533209.1	KLF12_N	40..237	CDD:410608	31/181 (17%)
		COG5048	<241..414	CDD:227381	54/224 (24%)
		C2H2 Zn finger	332..354	CDD:275368	10/21 (48%)
		C2H2 Zn finger	362..384	CDD:275368	7/21 (33%)
		zf-H2C2_2	376..401	CDD:463886	7/26 (27%)
		C2H2 Zn finger	392..412	CDD:275368	4/21 (19%)