DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lmd and glis2a

DIOPT Version :9

Sequence 1:	NP_732811.1	Gene:	lmd / 42717	FlyBaseID:	FBgn0039039	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	XP_009294691.1	Gene:	glis2a / 102725534	ZFINID:	ZDB-GENE-130102-1	Length:	446	Species:	Danio rerio

Alignment Length:	187	Identity:	97/187 - (51%)
Similarity:	121/187 - (64%)	Gaps:	10/187 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   424 PEAEPENEVIPLICRWTGCDEEFPHQQAFVEHIEKCHVDVRKGEDFSCFWLDCPRRYKPFNARYK 488
            ||...:.:   |.|||..|...|...|..|:|:...||...|...:.|.|..|.|:.:.||||||
Zfish   135 PEPSGDEQ---LACRWLKCHLLFESLQDLVDHVNDSHVKPEKASGYCCHWEGCARKGRGFNARYK 196

  Fly   489 LLIHMRVHSGEKPNKCPFPGCNKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKHQ 553
            :|||:|.|:.|||:.|  |.|:|:||||||||||.||||||:||.|.|:||.|.:||||||.||.
Zfish   197 MLIHIRTHTNEKPHHC--PTCHKSFSRLENLKIHTRSHTGEKPYICPYEGCNKRYSNSSDRFKHT 259

  Fly   554 RTHYDTKPYACQLPGCTKRYTDPSSLRKHVK--NHAL---RNANGQLRRKSAGGASV 605
            ||||..|||.|::.||.||||||||||||:|  .||:   |.|:.:..|..:..||:
Zfish   260 RTHYVDKPYCCKMVGCLKRYTDPSSLRKHIKAHGHAVVQDRAASPRTNRLESDTASL 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lmd	NP_732811.1	zf-H2C2_2	489..515	CDD:290200	13/25 (52%)
		C2H2 Zn finger	504..526	CDD:275368	15/21 (71%)
		C2H2 Zn finger	534..556	CDD:275368	14/21 (67%)
		C2H2 Zn finger	564..586	CDD:275368	16/23 (70%)
glis2a	XP_009294691.1	C2H2 Zn finger	188..204	CDD:275368	10/15 (67%)
		zf-H2C2_2	200..221	CDD:290200	11/22 (50%)
		COG5048	208..>285	CDD:227381	54/78 (69%)
		C2H2 Zn finger	212..232	CDD:275368	15/21 (71%)
		zf-H2C2_2	224..251	CDD:290200	18/26 (69%)
		C2H2 Zn finger	240..262	CDD:275368	14/21 (67%)
		C2H2 Zn finger	270..292	CDD:275368	16/21 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910