Protein Alignment lmd and gli2

DIOPT Version :10

• Sequence 1: NP_732811.1
• Gene: lmd / 42717
• FlyBaseID: FBgn0039039
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: XP_002943329.3
• Gene: gli2 / 100498653
• XenbaseID: XB-GENE-481810
• Length: 1474
• Species: Xenopus tropicalis
• Alignment Length: 914
• Identity: 227/914 - (24%)
• Similarity: 344/914 - (37%)
• Gaps: 301/914 - (32%)

  Fly    78 PDFSHLCFAAETPNSV----FSDCHNYAGQDQQ------QDSDQDDIVCAAAENTGMPYQQGQYT 132
            |..|.:.....:|:|:    |...|:|.....:      ..|....::.||   .|:...:..:.
 Frog    84 PVISDISLIRLSPHSLGTAEFGHAHHYVSPHMEHYLRSVHGSPTLSMISAA---RGLSPAEVAHE 145

  Fly   133 QLNREDIFRFEPEDIARLTGESELPGMLQHPQTPYTPY--------TPYTPYTPCSAQNSQYAVQ 189
            .|....||...|                  |.|..|.|        :..:||.....|:   |..
 Frog   146 HLKERGIFGLAP------------------PGTAPTEYCHQMAILASHASPYGELLVQS---AAA 189

  Fly   190 PANDSINL-------DIDYFNYDEINCQ-SKNQSPCSSPHLDAWL----------NFNLGEISAA 236
            .|.::.:|       |:..|:...:..: |:.::...||..||.:          |..:..|:.:
 Frog   190 AAGNTAHLHEYLTPMDVSRFSSPRVTPRLSRKRALSISPLSDASIDLQTMIRTSPNSLVAYINNS 254

  Fly   237 ASSSAASPKLGNVFEEQVKEEASPA-KLP----------------SMNSTFG-------TPKCIP 277
            .||||||...|::....:    ||| ..|                |:.|:||       :|...|
 Frog   255 RSSSAASGSYGHLSAGAI----SPAFSFPHPINPVAYQQLLSQQRSLTSSFGHAPLLHPSPTFAP 315

  Fly   278 MCASNYEDYANLYQQGSGYST-----ENYHNNMAQVVEKPNREHKAIWTIDELDELMLGEQQQFL 337
            .            |||:..|.     .|..:....|:.|.:.|.....|::::
 Frog   316 R------------QQGALTSANPAPPSNNSSTPDSVLNKGSSESAVSSTVNQV------------ 356

  Fly   338 QHHLQQQHLQEQQEQLHQPHGQEQQTQNCKDDLVNYLSDEFIKAEEFRSLDSDDDENYNEEEDDL 402
                    :.::.:...:..|.::.:.:..|.|.:.                         ::||
 Frog   357 --------IPKRSKVKMEDEGLQRDSPSPPDHLTDL-------------------------KEDL 388

  Fly   403 DNDVFAPPAESDPKPDSTCCDPEAEPENEVI-PLICRWTGCDEEFPHQQAFVEHIEKCHVDVRKG 466
            |.|                   |.:.|.:|| ...|.|.||..||..|...|.||...|:...|
 Frog   389 DKD-------------------ECKQEPDVIYETNCHWDGCSHEFDTQDQLVHHINNDHIHGEK- 433

  Fly   467 EDFSCFWLDCPRRYKPFNARYKLLIHMRVHSGEKPNKCPFPGCNKAFSRLENLKIHQRSHTGERP 531
            ::|.|.|.||.|..|||.|:|.|::|||.|:||||:||.|.||.||:|||||||.|.||||||:|
 Frog   434 KEFVCRWHDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCYKAYSRLENLKTHLRSHTGEKP 498

  Fly   532 YGCQYKGCLKAFSNSSDRAKHQ-RTHYDTKPYACQLPGCTKRYTDPSSLRKHVKN------HALR 589
            |.|:::||.|||||:||||||| |||.:.|||.|::||||||||||||||||||.      |..:
 Frog   499 YVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTK 563

  Fly   590 NANGQLRRKSA-------GGASVPPSGPKKAAKTRRHSESALVQRGVGAGVGVAVPSAPGDQRQH 647
            .....:.:|.:       ..||...||.:......|..|..|..|.:.....:...|:||.|
 Frog   564 KHRNDIIQKPSVTKENGDNEASAKLSGREHPNSAPREREDCLQARSIKTEDNMMHQSSPGGQ--- 625

  Fly   648 RSNSCSE---------------------------------------------ALLLQQHQQQQQQ 667
              :|||.                                             .|.|::|.....|
 Frog   626 --SSCSSEPSPYGIDSGVDVSLHGEGGLGELFGLEETSPVVDSTVSSGGAGIGLQLRKHGGTAVQ 688

  Fly   668 QQQQQKQHQPENERTTDRSNCG-------------TGVAANNNSMN-------------FNELS- 705
            :.:|.|:.:.:    |.:.:|.             ..::||..|::             ..|||
 Frog   689 RLEQLKKEKLK----TVKDSCSFMNPAPPVRNTRLPTISANGPSLDALGVPSNVLLGGRAAELSM 749

  Fly   706 NCIVIIEH-NQSGGPAGPATLATATATTTATATYGNGNMAPAPETEVLSVCS--GGGSSNSNS-- 765
            |.:.::.| |:.....|      :|.::..|:...:| ::|...:...|..|  ||..:||:|
 Frog   750 NEVTVLNHLNERRDSTG------STVSSAYTSRRSSG-ISPYFSSRRSSETSQFGGRLNNSSSAD 807

  Fly   766 -------NNNRYNANINQLSELEQLL----------------TTAKPTGTPAASANGISLANNNG 807
                   :.:|.::..:|.|.|..||                .|..|..||..:.:.|||.|...
 Frog   808 SYDPISTDASRRSSEASQHSGLPNLLNLTPAQQYRLKAKYAAATGGPPPTPLPNMDRISLRNKLS 872

  Fly   808 RANG 811
            ..:|
 Frog   873 LMDG 876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lmd	NP_732811.1	SFP1	<493..585	CDD:227516	69/92 (75%)
		C2H2 Zn finger	504..526	CDD:275368	15/21 (71%)
		C2H2 Zn finger	534..556	CDD:275368	16/22 (73%)
		C2H2 Zn finger	564..586	CDD:275368	19/27 (70%)
gli2	XP_002943329.3	C2H2 Zn finger	441..463	CDD:275368	12/21 (57%)
		SFP1	<465..555	CDD:227516	67/89 (75%)
		C2H2 Zn finger	471..493	CDD:275368	15/21 (71%)
		C2H2 Zn finger	501..524	CDD:275368	16/22 (73%)
		C2H2 Zn finger	532..553	CDD:275368	18/20 (90%)