Protein Alignment CG6688 and Nherf2

DIOPT Version :10

• Sequence 1: NP_651110.1
• Gene: CG6688 / 42716
• FlyBaseID: FBgn0039038
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_075542.2
• Gene: Nherf2 / 65962
• MGIID: 1890662
• Length: 337
• Species: Mus musculus
• Alignment Length: 161
• Identity: 47/161 - (29%)
• Similarity: 73/161 - (45%)
• Gaps: 24/161 - (14%)

  Fly    10 STSNEDGQHGDGSSVRLLRIPRAA---PAMENYGFQLTRSKWDPYPWVCEVAAGTPAALCGLKPG 71
            |..::.||.......|.|| ||..   ...:.|||.|...|..|..::..|..|:||:..||:..
Mouse   130 SLGSDTGQKDVNGPPRELR-PRLCHLRRGPQGYGFNLHSDKSRPGQYIRSVDPGSPASHSGLRAQ 193

  Fly    72 DCVLEVNGNDVLGLRVSEIAKMVKSQKDCVTILCWNSECDKDCDTNSICCAPMPTSLRRLSLV-- 134
            |.::||||.:|.|||.:|:...:|:|:|...:|..:.|.|:              ..:||.::
Mouse   194 DRLIEVNGQNVEGLRHAEVVARIKAQEDEARLLVVDPETDE--------------HFKRLRVIPT 244

  Fly   135 LESILRLVECPVCGVTISPPAMQCQNGHLLC 165
            .|.:...:..||...| ||..:   ||..:|
Mouse   245 EEHVEGPLPSPVTNGT-SPAQL---NGGSVC 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6688	NP_651110.1	PDZ_canonical	25..104	CDD:483948	30/81 (37%)
		RING-HC_SIAHs	143..179	CDD:438233	8/23 (35%)
Nherf2	NP_075542.2	PDZ_NHERF-like	10..89	CDD:467249
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	112..145		3/14 (21%)
		PDZ_NHERF-like	150..229	CDD:467249	27/78 (35%)
		EBP50_C	232..337	CDD:462654	12/58 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	242..337		9/34 (26%)