DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6688 and Pdzd2

DIOPT Version :9

Sequence 1:	NP_651110.1	Gene:	CG6688 / 42716	FlyBaseID:	FBgn0039038	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_038959013.1	Gene:	Pdzd2 / 65034	RGDID:	619958	Length:	2818	Species:	Rattus norvegicus

Alignment Length:	500	Identity:	111/500 - (22%)
Similarity:	164/500 - (32%)	Gaps:	145/500 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GFHSTSNEDGQHGDGSSVRLLRIPRAA------PAMENYGFQLTRSKWDPYPWVCEVAAGTPAAL 65
            |....::.....||..|.::.|..|.|      |.|.|   .|.|...|         .|.|
  Rat  1664 GIMDVTSTSSNMGDSQSSQMTRHCRNAPFVLGNPDMVN---DLGRDLLD---------EGAP--- 1713

  Fly    66 CGLKPGDCVLEV-------------NGNDVLG-LRVSE---IAKMVKSQKDCV--TILCWNSECD 111
               |.|.....|             ||..||. |.::|   :..:::..|...  .||.|..|.:
  Rat  1714 ---KEGAAAASVMRSVFALGAEGPKNGEAVLADLHIAERGNLEDLLQKPKTISRRPILTWFKEIN 1775

  Fly   112 KDCDTNSICCAPMPTSLRRLSLVLESILRLVEC-PVCGVTI--SPPAMQCQNGHLLCVDCRIRSE 173
            ||...:.:...........|:|...|...:|.. ...|||:  |||:.|             :|:
  Rat  1776 KDSQGSHLRSTSEKEQSSMLALGPGSKANMVNTGHRKGVTVPKSPPSRQ-------------KSQ 1827

  Fly   174 RCPVCRDFYTPRRALLAEQIFLTIANAFEMCRSENKLRQKLFAGITRPVVGRQDRITGQDTWRKR 238
            .          .:.|..:....|:.|. :..:...||::....|...|.|  ...|:.:.:....
  Rat  1828 E----------NKDLPPKSPVETLGNC-QKPKCSPKLKRLNSKGKASPEV--PVAISTKGSRNDH 1879

  Fly   239 RPVLP----TNKFLTKLLEGCAYSTDNLSPSNAA--------------------TLLRTNTTDVA 279
            |..||    ::|..:|.:....:..|...|.|.|                    ..|||:.:|
  Rat  1880 RKTLPSPQASHKMFSKAVSHRLHIADQEEPKNTAGDTPKPPQCVPESKPPQAALGSLRTSASD-- 1942

  Fly   280 GDSSEIPARTSPVTATP--PE-----RTTMHATLDANAAHPSLSTNDLQ-QEGVKPNAEGVDEES 336
               :.|...|||:|:..  ||     |..|...|:::.:.|:.|.:... .||..|:|     .|
  Rat  1943 ---TSIRTFTSPLTSPKLLPEQGANSRFHMAVYLESDTSCPTTSRSPRSGPEGKAPHA-----NS 1999

  Fly   337 GTNSSHISATSLHGPPLPASVSPGINESSGLQPVR----IPPVTPSQ------------DLPQQV 385
            |:.|...|..||        ...||.:|....|.|    :...|..|            |.||:.
  Rat  2000 GSASPPASRASL--------ALAGIRQSKQFTPGRADLLVSEATQPQGICEKGAEKKVSDPPQRT 2056

  Fly   386 VQTKPASL-LYRCP---CKLQDPQDPAKD---LHQNCCYKSAFRL 423
            .|.|...: ..|.|   |..:.|:...|.   ...||..|||.||
  Rat  2057 NQLKIVEISSERVPKNACGDRPPESDRKGGFLTQNNCQEKSAIRL 2101

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6688	NP_651110.1	PDZ_signaling	24..104	CDD:238492	21/104 (20%)
Pdzd2	XP_038959013.1	PDZ_signaling	335..416	CDD:238492
		PDZ_signaling	590..671	CDD:238492
		PDZ_signaling	729..813	CDD:238492
		PHA03247	<985..1446	CDD:223021
		PDZ_signaling	2603..2677	CDD:238492
		PDZ_signaling	2731..2813	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900