DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6688 and Slc9a3r1

DIOPT Version :9

Sequence 1:	NP_651110.1	Gene:	CG6688 / 42716	FlyBaseID:	FBgn0039038	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_067605.1	Gene:	Slc9a3r1 / 59114	RGDID:	708538	Length:	356	Species:	Rattus norvegicus

Alignment Length:	148	Identity:	36/148 - (24%)
Similarity:	59/148 - (39%)	Gaps:	30/148 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 YGFQLTRSKWDPYPWVCEVAAGTPAALCGLKPGDCVLEVNGNDVLGLRVSEIAKMVKSQKDCVTI 103
            |||.|...|.....::..|..|:||...||..||.::||||.:|......::...:::..:.|.:
  Rat    24 YGFHLHGEKGKVGQFIRLVEPGSPAEKSGLLAGDRLVEVNGENVEKETHQQVVSRIRAALNAVRL 88

  Fly   104 LCWNSECDKDCDTNSICCAPMPTSLRRLSL-VLESILRLVECPVCGVTISPPAM----------Q 157
            |..:.|.|:              .|::|.: :.|.:||..|   ......|||.          :
  Rat    89 LVVDPETDE--------------QLKKLGVPIREELLRAQE---KSEHTEPPAAADTKKAGDQNE 136

  Fly   158 CQNGHLLCVDCRIRSERC 175
            .:..||  ..|.:|...|
  Rat   137 AEKSHL--ERCELRPRLC 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6688	NP_651110.1	PDZ_signaling	24..104	CDD:238492	19/64 (30%)
Slc9a3r1	NP_067605.1	PDZ_signaling	12..91	CDD:238492	20/66 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	113..142		4/31 (13%)
		PDZ_signaling	149..228	CDD:238492	1/4 (25%)
		EBP50_C	232..356	CDD:286142
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	265..356
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14191
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000