DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6688 and loco

DIOPT Version :9

Sequence 1:	NP_651110.1	Gene:	CG6688 / 42716	FlyBaseID:	FBgn0039038	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_732773.1	Gene:	loco / 42672	FlyBaseID:	FBgn0020278	Length:	1541	Species:	Drosophila melanogaster

Alignment Length:	345	Identity:	61/345 - (17%)
Similarity:	110/345 - (31%)	Gaps:	134/345 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 DFYTPRRALLAEQIFLTIANAFEMCRSENKL------RQKLFAGITRPVVGR------QDRITGQ 232
            |...|.:.|..:::.:....||::...:.|:      .:|....:.||::.:      |.::..:
  Fly  1124 DVQQPSQILAGKEVVIERRVAFKLDLPDPKVISVKSKPKKQLHEVIRPILSKYNYKMEQVQVIMR 1188

  Fly   233 DTW------------------------------------RKRRPVLP---------TNKFLTKLL 252
            ||.                                    ::.:|:.|         |||...:||
  Fly  1189 DTQVPIDLNQPVTMADGQRLRIVMVNSDFQVGGGSSMPPKQSKPMKPLPQGHLDELTNKVFNELL 1253

  Fly   253 EG---------------CAYSTDNLSPSNAATL---------------------LRTNTTDVAGD 281
            ..               |:..: |.:||..::|                     |:..:|..:..
  Fly  1254 ASKADAAASEKSRPVDLCSMKS-NEAPSETSSLFERMRRQQRDGGNIPASKLPKLKKKSTSSSQQ 1317

  Fly   282 SSEIPARTSPVTATP--PERTTMHATLDANAAHPSLSTNDLQQEGVK-PNAEGVDEESGT----- 338
            |.|  |.|:...|.|  |....:.|.:............|...||:| .....::::.||
  Fly  1318 SEE--AATTQAVADPKKPIIAKLKAGVKLQVTERVAEHQDELLEGLKRAQLARLEDQRGTEINFD 1380

  Fly   339 ------NSSHISATSLHGPPLPASVSPGINESSGLQPVRIPPVTPSQDLPQQVVQ------TKPA 391
                  |..::|          |:||......:.|.||...|.||: ::||...:      .:|.
  Fly  1381 LPDFLKNKENLS----------AAVSKLRKVRASLSPVSKVPATPT-EIPQPAPRLSITRSQQPV 1434

  Fly   392 SLLYRCPCKLQDPQDPAKDL 411
            |     |.|:.  |:|..||
  Fly  1435 S-----PMKVD--QEPETDL 1447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6688	NP_651110.1	PDZ_signaling	24..104	CDD:238492
loco	NP_732773.1	PDZ_signaling	69..145	CDD:238492
		PTB_RGS12	251..391	CDD:269984
		RGS_R12-like	828..941	CDD:188661
		RGS12_RBD	1073..1145	CDD:176412	3/20 (15%)
		RBD	1144..1213	CDD:128731	9/68 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900