DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6688 and SIAH3

DIOPT Version :10

Sequence 1:NP_651110.1 Gene:CG6688 / 42716 FlyBaseID:FBgn0039038 Length:424 Species:Drosophila melanogaster
Sequence 2:NP_942146.2 Gene:SIAH3 / 283514 HGNCID:30553 Length:269 Species:Homo sapiens


Alignment Length:81 Identity:17/81 - (20%)
Similarity:32/81 - (39%) Gaps:21/81 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 SSVRLLRIPRAAPAMENYGFQLTRS----KWDPYP-WVCEVAAGTPAALCGLKPGDCVL------ 75
            :::.|:..|..|... .|..:|.|:    ||:..| .|.|.....      :..|||::      
Human   185 ATMMLIGTPTQADCF-TYRLELNRNHRRLKWEATPRSVLECVDSV------ITDGDCLVLNTSLA 242

  Fly    76 ---EVNGNDVLGLRVS 88
               ..||:..:|:.::
Human   243 QLFSDNGSLAIGIAIT 258

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6688NP_651110.1 PDZ_canonical 25..104 CDD:483948 17/78 (22%)
RING-HC_SIAHs 143..179 CDD:438233
SIAH3NP_942146.2 Sina 133..259 CDD:239753 17/81 (21%)
Blue background indicates that the domain is not in the aligned region.

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