Protein Alignment CG6688 and nrfl-1

DIOPT Version :10

• Sequence 1: NP_651110.1
• Gene: CG6688 / 42716
• FlyBaseID: FBgn0039038
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_741479.1
• Gene: nrfl-1 / 177736
• WormBaseID: WBGene00006438
• Length: 608
• Species: Caenorhabditis elegans
• Alignment Length: 353
• Identity: 70/353 - (19%)
• Similarity: 121/353 - (34%)
• Gaps: 90/353 - (25%)

  Fly    25 RLLRIPRAAPAMENYGFQLTRSKWDPYPWVCEVAAGTPAALCGLKPGDCVLEVNGN---DVLGLR 86
            ||..:.:..|..| :||.|...:...: ::..|.||......||:.|..::.|||.   ...|.:
 Worm   283 RLAELNKGTPDQE-FGFNLHAERGRGH-FIGTVDAGGIGEKAGLEAGQRIVGVNGQLIYPTTGHK 345

  Fly    87 VSEIAKMVKSQKDCVTILCWNSECDKDCDTNSICCAPMPTSLRRLSLVLESILRLVECPVCGV-- 149
              |:..::|......|:|..:.:.||....::|..:            .:::.|:...||..|
 Worm   346 --EVVALIKKDTMKTTLLVASEDVDKYHKDHNIAYS------------WDNVERVDTRPVINVET 396

  Fly   150 -----TISPPAMQCQNGH----LLCVDCRIRSERCPVCRDFYTPRRALLAEQIFLTIAN---AFE 202
                 .:|.|.   .||:    |.....::..|| .:.:...|.|..        ||.|   |::
 Worm   397 HHHHEEVSVPK---SNGYDVPPLNPHSIQVNEER-EISKMTTTTRTE--------TITNSNSAYQ 449

  Fly   203 MCRS-------------ENKLRQKLFAGITRPVVGRQDRITGQDTWRKRRPVLPTNKFLTKLLEG 254
            ...|             .|.|..::|..:..|.|          |......|||
 Worm   450 YKESSTAYDAYATPPVDSNDLMDEVFGRVNLPGV----------TMSSHTEVLP----------- 493

  Fly   255 CAYSTDNLSPSNAATLLRTNTTDVAGDSSEIPARTSPVTATPPERTTMHATLDANAAH--PSLST 317
               .||::|..::.:..|.:..||......:|   |..|.:..:......|...:..|  ||..:
 Worm   494 ---PTDDISSVSSLSSHRESAVDVPVSHQYVP---SYATESHQKHEQHSQTHHHHHQHQQPSPLS 552

  Fly   318 NDLQQEGVKPNAEGVDEESGTNSSHISA 345
            |.........:..|.|::   :..|:||
 Worm   553 NGSSHGYAASSTSGYDDD---DIYHLSA 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6688	NP_651110.1	PDZ_canonical	25..104	CDD:483948	20/81 (25%)
		RING-HC_SIAHs	143..179	CDD:438233	10/46 (22%)
nrfl-1	NP_741479.1	PDZ_NHERF-like	283..364	CDD:467249	21/84 (25%)