Protein Alignment CG6688 and USH1C

DIOPT Version :9

• Sequence 1: NP_651110.1
• Gene: CG6688 / 42716
• FlyBaseID: FBgn0039038
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: XP_016872564.1
• Gene: USH1C / 10083
• HGNCID: 12597
• Length: 956
• Species: Homo sapiens
• Alignment Length: 492
• Identity: 95/492 - (19%)
• Similarity: 165/492 - (33%)
• Gaps: 122/492 - (24%)

  Fly     1 MRKSAGGFHSTSNED--------GQHGDGSSVRLLRIPRAAPAMENYGFQLTRSKWDPYPWVCEV 57
            :|.|.|...:..|::        |..|.|.|:      .:.|..:            |..::..|
Human   195 VRGSLGSPGNRENKEKKVFISLVGSRGLGCSI------SSGPIQK------------PGIFISHV 241

  Fly    58 AAGTPAALCGLKPGDCVLEVNGNDVLGLRVSEIAKMVKSQKDCVTILCWNSECDKDCDTNSICCA 122
            ..|:.:|..||:.||.::||||.|...|...|...::||.:..               |.||..|
Human   242 KPGSLSAEVGLEIGDQIVEVNGVDFSNLDHKEAVNVLKSSRSL---------------TISIVAA 291

  Fly   123 ---------------PMPTSLRRLSLVLESILRLVECPVCGVTISPPAMQCQNGHLLCVDC---- 168
                           .....|:|..|:::..|.:....:..   ....|:.|....:....
Human   292 AGRELFMTDRERLAEARQRELQRQELLMQKRLAMESNKILQ---EQQEMERQRRKEIAQKAAEEN 353

  Fly   169 -RIRSERCPVC-----------RDFYTPRRALLAEQI-----------------FLTIANAFEMC 204
             |.|.|...:.           .|:.:..:.||.:.|                 |......|...
Human   354 ERYRKEMEQIVEEEEKFKKQWEEDWGSKEQLLLPKTITAEVHPVPLRKPKSFGWFYRYDGKFPTI 418

  Fly   205 RSENKLRQKLFAGITRPV-VGRQDRITGQDTWRKRRPVLPTNKFL--TKLLEGCAYS-TDNLSPS 265
            |.:.|.::|...|..:.: ..:::....|..::::..:|...|.|  .:|.:..:.: .::|..|
Human   419 RKKGKDKKKAKYGSLQDLRKNKKELEFEQKLYKEKEEMLEKEKQLKINRLAQEVSETEREDLEES 483

  Fly   266 N-----AATLLRTNTTDVAGDSSEIPARTSPVTATPPERTTMHATLDANAAHPSLSTNDLQQEGV 325
            .     ...|.:|....::...:||...|:.....||..:.:...|...|....|.|.||....:
Human   484 EKIQYWVERLCQTRLEQISSADNEISEMTTGPPPPPPSVSPLAPPLRRFAGGLHLHTTDLDDIPL 548

  Fly   326 --------KPNAEGV-DEESGTNSSHISATSLHGPP-LP------ASVSPGINESSGLQPVRIPP 374
                    .|:|..| .....:|..|    .:..|| ||      ||.||.:..:....|:..||
Human   549 DMFYYPPKTPSALPVMPHPPPSNPPH----KVPAPPVLPLSGHVSASSSPWVQRTPPPIPIPPPP 609

  Fly   375 VTPSQDL-PQQVVQTKPASLLYRCPCKLQDPQDPAKD 410
            ..|:||| |.:.:.:.....|...|.:..|..:|.:|
Human   610 SVPTQDLTPTRPLPSALEEALSNHPFRTGDTGNPVED 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6688	NP_651110.1	PDZ_signaling	24..104	CDD:238492	18/79 (23%)
USH1C	XP_016872564.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900