DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34375 and Patj

DIOPT Version :9

Sequence 1:	NP_001163693.1	Gene:	CG34375 / 42715	FlyBaseID:	FBgn0085404	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_477342.1	Gene:	Patj / 44100	FlyBaseID:	FBgn0067864	Length:	871	Species:	Drosophila melanogaster

Alignment Length:	322	Identity:	58/322 - (18%)
Similarity:	105/322 - (32%)	Gaps:	122/322 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   280 IKVQHQEAAVEHFSEEGHNNMLVKPKLKLSKKSWRIT---------GPD----QDGLRCDE---- 327
            |:|..:...|:..|.:|::|   ...::|.|||.::.         ||.    |..:..::
  Fly   362 IRVNDRIIEVDGQSLQGYSN---HQAVELLKKSGQVVNLRLERYLRGPKFEQLQQAIAANDKLPS 423

  Fly   328 --------------VATINNGVQVQEQQQQQERQQLGHEKSASSESEYQNYHCPTGKSCSSHSYQ 378
                          |||.::.....             .:|.:.|.|.:....|       .::.
  Fly   424 SAPGTPSRAPMPTPVATTSSATTTP-------------SRSITRELEEEALPAP-------EAFM 468

  Fly   379 LGQPVANKLSTVAM-------QALAVVENSGGAS-------LSAGSHKQAPAAGV--------NQ 421
            ...|....::|..:       |.:||.::..|::       :......:|..:||        :.
  Fly   469 TTPPSVTTMTTTTLSSFGAGKQLVAVRDSLDGSTKIIPTEVVPLADKTEAKNSGVITRHKYYTDP 533

  Fly   422 ELPLEAGSIGRREWQLLRHLSGDHRLAVLQI----YGTFGERLHVRPQLPLEGVACLRLSEESST 482
            ||..:|.:...|:||.:  :..|..:.|.||    .|..|        :.|||...:....|
  Fly   534 ELSDDAETEIIRKWQKI--VGSDVEVIVAQIKKFAVGGLG--------ISLEGTVDVEGGRE--- 585

  Fly   483 FGHVRVHTFFLAVIAIGGGDEHAVFLWHLDHLPHGP--------TFETVIETPGHRFLGPAH 536
               ||.|.:..::                  ||.||        :.:.::|..|.|.||..|
  Fly   586 ---VRPHHYIRSI------------------LPDGPVGVNGVLRSGDELLEVNGERLLGMNH 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34375	NP_001163693.1	PDZ	13..86	CDD:238080
CG34375	NP_001163693.1	RING	129..168	CDD:238093
Patj	NP_477342.1	L27	12..70	CDD:295425
		PDZ_signaling	154..226	CDD:238492
		PDZ_signaling	318..400	CDD:238492	10/40 (25%)
		PDZ_signaling	557..643	CDD:238492	22/102 (22%)
		PDZ_signaling	726..807	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900