Protein Alignment CG34375 and LOC1273647

DIOPT Version :10

• Sequence 1: NP_001163693.1
• Gene: CG34375 / 42715
• FlyBaseID: FBgn0085404
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_312649.5
• Gene: LOC1273647 / 1273647
• VectorBaseID: AGAMI1_007076
• Length: 561
• Species: Anopheles gambiae
• Alignment Length: 599
• Identity: 143/599 - (23%)
• Similarity: 241/599 - (40%)
• Gaps: 183/599 - (30%)

  Fly    12 NGTLGLNLSRAPWDPYPWVSGVQAKSSAERGGVRLGDTLLELNGADVLGLKISELANRLQDHWQS 76
            :|:.|.:|:|:.||||||||||.|.|.||..|:::||.:||:|..||||::|:|:|..:    ::
Mosquito    63 DGSCGFHLTRSKWDPYPWVSGVDADSPAEVTGLKVGDCVLEVNNEDVLGMRIAEVAGMV----RA 123

  Fly    77 GAEVVTLMMWRQQANIDPNEDPAEASHAVQHGINQQSLQKFATCLQHISQLLECPVCLEVIKPPG 141
            .|::|||::|      ....:||....::..|....:|::....:|.|...||||||.:.|.||.
Mosquito   124 KADIVTLLLW------STGMEPACNPESLCCGPMPINLERLTASMQTIVAALECPVCFDTIPPPV 182

  Fly   142 WQCCNGHVLCNNCRSRSVKCPVCRVPLGPR---GRCLLSDKLFTLLAESFPCDGGKTNKVAASQG 203
            :||.|||::|:.||.|:.:|.:||    .|   ||.||:::::..:.|:|....|...|:
Mosquito   183 FQCQNGHLVCSRCRVRAERCAICR----ERYTVGRSLLAEQVYQSITEAFNLREGTDGKL----- 238

  Fly   204 HGKLSSVNKCTNEYHNQPKMALAKTSSGKSKCGKQISRQLETVLVDQSPREIRRKSQQGQEQEQA 268
            ..:|... :||    .|||.|        |.|.                   |:||..|.:....
Mosquito   239 RERLFGA-RCT----RQPKRA--------SSCD-------------------RKKSPYGSDSHLV 271

  Fly   269 VQEAVLPRCT---LIKVQHQEAAVEHFSEEGHNNMLVKPKLKLSKKSWRITGPDQDG-------- 322
            .....:...|   |.::..:.::|::.|:.|.....::|             ||..|
Mosquito   272 PSGRPIHSHTHKFLARIMGKASSVDNLSKHGGGGQHMQP-------------PDVVGDLQGSKGK 323

  Fly   323 ---LRCDEVATINNGVQVQEQQQQQERQQLGHEKSASSESEYQNYHCPTGK------SCSSHSYQ 378
               |...|:...:|.|.|                          ..||:..      |.|.:|..
Mosquito   324 SLSLSTSEIFKRDNSVSV--------------------------LRCPSANRLAPELSGSYNSLA 362

  Fly   379 LGQPVANKLSTVAMQALAVVENSGGASLSAGSHKQAPAAGVNQELPLE------------AGSIG 431
            :.:|.::....|::::|:.:                |..|:...:|:.            |..|.
Mosquito   363 IRRPTSSMSCNVSVESLSSI----------------PENGIQLTVPVRPHSYHCPCGEYCADLIA 411

  Fly   432 RREWQLLRHLSGDHRLAVLQIYGTFGERLHVRPQLPLEGVAC-----------LRLSEESSTFGH 485
            ..|.|  .|::..||..|:. :||....:.:.|:.|::. ||           |:|..::||.|.
Mosquito   412 APELQ--DHVTVHHRTPVIS-FGTASAEISLPPRTPVDN-ACLLLLLDGHKFWLKLISDTSTIGD 472

  Fly   486 VRVHTFFLAVIAIGGGDEHAVFLWHLDHLPHGPTFETVIETPG-HRFLGPAHSLRC--------S 541
            :     ||:.:..|..::...:           ..|.::...| ...||.....|.        |
Mosquito   473 I-----FLSALLEGSPEQSKNY-----------ALEVIVRKAGFDHILGKELISRSEVYSMVDKS 521

  Fly   542 WPEI--RASGQFLT 553
            |.::  ..||.|.|
Mosquito   522 WNDLVNSKSGVFYT 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34375	NP_001163693.1	PDZ_canonical	11..81	CDD:467153	32/68 (47%)
		RING-HC_SIAHs	128..165	CDD:438233	19/36 (53%)
LOC1273647	XP_312649.5	None