Protein Alignment Nha2 and NHA1

DIOPT Version :9

• Sequence 1: NP_001247251.1
• Gene: Nha2 / 42710
• FlyBaseID: FBgn0263390
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_013239.1
• Gene: NHA1 / 850829
• SGDID: S000004128
• Length: 985
• Species: Saccharomyces cerevisiae
• Alignment Length: 426
• Identity: 85/426 - (19%)
• Similarity: 146/426 - (34%)
• Gaps: 144/426 - (33%)

  Fly   309 VLYANLGLANFEG-YQKFELFLREMALINIMLLAGL-GLDGDAFKRLWF----------MILRLT 361
            |.||.:|:  |.. :....|:::|...|....:||: ||........||          :.|.:|
Yeast    14 VAYACVGV--FSSIFSLVSLYVKEKLYIGESTVAGIFGLIVGPVCLNWFNPLKWGNSDSITLEIT 76

  Fly   362 LLPTIVEVAAIAGLANLTLSMP-------WL-------------WGIALGLVITAVSPNVVVTVM 406
            .:...:::.|:|      :.:|       |:             | :.:||.:..:.|
Yeast    77 RIVLCLQIFAVA------VELPRKYMLKHWVSVTMLLLPVMTAGW-LIIGLFVWILIP------- 127

  Fly   407 LKLKEDRLGLNSGIHTLIYAMTTCNDVVAIFMFGVIISVIFS--TTSLTQQVLQGPIGIGIGLVF 469
                    |||.....||.|..|..|.:   :...::|..|:  .....:.:|....|...|:.|
Yeast   128 --------GLNFSASLLISACITATDPI---LAQSVVSGKFAQRVPGHLRNLLSAESGCNDGMAF 181

  Fly   470 GYLYGSMLQYLPSRNATYANGLRFV-----LTILGGTIAVMGSRVIGYTSAGALGCVTTAFIARI 529
            .:|:.||...|..     .||...|     :|||...:               .||:...||..:
Yeast   182 PFLFLSMNLILHP-----GNGREIVKDWICVTILYECL---------------FGCLLGCFIGYV 226

  Fly   530 GWRREETRLTPQQLQAQQIASVPKRLDLMWKFLKPVSFALIGKEINFNVLQGHVIGYGALLVLVG 594
            |      |:|.:..:.:.|......|    .|...::|...|        .|.::|...|||
Yeast   227 G------RITIRFAEKKNIIDRESFL----AFYVVLAFMCAG--------FGSILGVDDLLV--- 270

  Fly   595 SLFRLAFAYLSTYG--GNLSRKER--------------AYITISGFPKATVQAALGPVALDMARA 643
                 :||..:|:.  |..|:|.:              ||....|......|...|.:..::.|
Yeast   271 -----SFAAGATFAWDGWFSQKTQESNVSTVIDLLLNYAYFIYFGAIIPWSQFNNGEIGTNVWR- 329

  Fly   644 ASVASPEQLALAGNLLIISVLAIIFTAPLGAILMLR 679
                          |:|:|:: :||...:.|:::||
Yeast   330 --------------LIILSIV-VIFLRRIPAVMILR 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha2	NP_001247251.1	Na_H_Exchanger	279..686	CDD:294713	85/426 (20%)
NHA1	NP_013239.1	c_cpa1	2..923	CDD:273295	85/426 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900