Protein Alignment Nha2 and slc9a3.1

DIOPT Version :9

• Sequence 1: NP_001247251.1
• Gene: Nha2 / 42710
• FlyBaseID: FBgn0263390
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_001106944.1
• Gene: slc9a3.1 / 568258
• ZFINID: ZDB-GENE-060503-545
• Length: 832
• Species: Danio rerio
• Alignment Length: 533
• Identity: 105/533 - (19%)
• Similarity: 171/533 - (32%)
• Gaps: 183/533 - (34%)

  Fly   233 KWWLYIRSHWVNTSELVALLAIFLGLWAMGWVLL--------PEYSQPPTVIMRIAFLFVGAQIS 289
            ||      |.|.|..||||.....||..:..:.|        ||                    |
Zfish    50 KW------HHVETPYLVALWVFVAGLAKLSVIQLNHSITGVFPE--------------------S 88

  Fly   290 GILVTFVHLPDMLGMLFFGVLYANLGLANFEGYQKFELFLREMALINIMLLAGLGLDGDAF--KR 352
            |:|:       :||.:..|::.         |..|.:.|....:.....||..:.||...|  .:
Zfish    89 GLLI-------ILGFILGGIVV---------GADKAQTFKLLPSTFFYYLLPQIILDASYFMPNK 137

  Fly   353 LWFMILRLTLLPTIVEV---AAIAGLANLTLSMPWLWG-----------------IALGLVITAV 397
            |:|..|...|:..|...   ||..||:        |||                 :..|.:|.||
Zfish   138 LFFRNLGAILIYAIFGTCWNAAAVGLS--------LWGCHEAGAMGDLNIGLLQFLLFGGLIAAV 194

  Fly   398 SPNVVVTVMLKLKEDRLGLNSGIHTLIYAMTTCNDVVAIFMFGVIISVIFSTTSLTQQVLQGPIG 462
            .|..|:.|.     :.:.:|..:..|::..:..||.|.:.::               .|..|.:.
Zfish   195 DPVAVIAVF-----EEVHVNEVLFILVFGESLLNDGVTVVLY---------------NVFDGFVS 239

  Fly   463 IGIGLVFGYLYGSMLQYLPSRNATYANGL-RFVLTILGGTIAVMGSRVIGYTSAGALGCVT---- 522
            :|         |.|:.     .|....|: .||:...||:.       :|...|..|..:|
Zfish   240 LG---------GPMID-----AAEIFKGICSFVVVAFGGSF-------VGVAFAILLSLLTRCTK 283

  Fly   523 ------TAFIARIGWRREETRLTPQQLQAQQIAS-----------VPKRLD--------LMWKFL 562
                  ..|:..:|:.   :.||.:.|....|.|           :...:|        ...|.|
Zfish   284 HVQIIEAGFVFLVGYL---SYLTVEMLSLSAILSTTFCGVCCQKYINANMDERSVTTVRHAMKML 345

  Fly   563 KPVSFALIGKEINFNVLQGHV----IGYGALLVLVGSLFRLAFAYLSTYGGNLSRK------ERA 617
            ...|..:|...:....:...:    .|:..|.:|...::|:...::.|:..|..|.      ::.
Zfish   346 ANGSETMIFLFLGVTAIDTEIWVWNTGFILLTLLFIFIYRIIGVFMFTWMLNKFRLVPVELIDQV 410

  Fly   618 YITISGFPKATVQAALGPVALDMARAASVAS-PEQLALAGNLLIISVLAIIFTAPLGAILMLRLA 681
            .::..|.        .|.||..:|.....:: ||:..:....||:    :.||..|....|..|.
Zfish   411 VMSYGGL--------RGAVAYGLAAMLDESTIPEKKLMISTTLIV----VYFTVILQGTTMKPLV 463

  Fly   682 PYWLK-----HGD 689
             .|||     |.|
Zfish   464 -QWLKVKRAAHSD 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha2	NP_001247251.1	Na_H_Exchanger	279..686	CDD:294713	87/469 (19%)
slc9a3.1	NP_001106944.1	b_cpa1	50..563	CDD:273294	105/533 (20%)
		Na_H_Exchanger	60..465	CDD:279355	94/505 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900