Protein Alignment Nha2 and Slc9a9

DIOPT Version :10

• Sequence 1: NP_001247251.1
• Gene: Nha2 / 42710
• FlyBaseID: FBgn0263390
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_001258367.1
• Gene: Slc9a9 / 363115
• RGDID: 1560736
• Length: 644
• Species: Rattus norvegicus
• Alignment Length: 408
• Identity: 84/408 - (20%)
• Similarity: 148/408 - (36%)
• Gaps: 101/408 - (24%)

  Fly   326 ELFLREMALINIMLLAGLGLDGDAFKRLWFM----ILRLTLLPTIVEVAAIAGLANLTLSMPWLW 386
            |:|. .:.|..|:..||..|.    ||.:|.    ||....|.|.:....| ||.        ::
  Rat   132 EIFF-NVLLPPIIFHAGYSLK----KRHFFQNLGSILTYAFLGTAISCVVI-GLI--------MY 182

  Fly   387 G---------------------IALGLVITAVSPNVVVTVMLKLKEDRLGLNSGIHTLIYAMTTC 430
            |                     :..|.:::|..|..|:.:..:|..|     ..::||::..:..
  Rat   183 GFVKAMVHAGQLKSGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVD-----PDLYTLLFGESVL 242

  Fly   431 NDVVAIFMFGVIISV--------IFSTTSLTQQVLQGPIGIGIGLVFG-YLYGSMLQYLPSRNAT 486
            ||.||| :....||:        .|.|.:..|.|     |..:|:..| :..||....:.:....
  Rat   243 NDAVAI-VLTYSISIYSPKENPNAFDTAAFFQSV-----GNFLGIFAGSFAMGSAYAVVTALLTK 301

  Fly   487 YANGLRFVLTILGGTIAVMGSRVIGYTSAGALGCVTTAFIARIGWRREETRLTPQQLQAQQIASV 551
            :.....|.:...|....:..|..:...:||..|.|...|..          :|........::|.
  Rat   302 FTKLREFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCG----------VTQAHYTYNNLSSD 356

  Fly   552 PK-RLDLMWKFL----KPVSFALIGKEINFNVLQGHVIGYGALLVLVGSLFRLAFA-----YLST 606
            .| |...:::|:    :.|.|..:|  :.....|.|:  :.||.:| |:...:..|     |..:
  Rat   357 SKLRTKQLFEFMNFLAENVIFCYMG--LALFTFQNHI--FNALFIL-GAFLAIFVARACNIYPLS 416

  Fly   607 YGGNLSRKERA------YITISGFPKATVQAALGPVALDMARAASVASPEQLALAGNLLIISVLA 665
            :..||.||::.      .:..||.        .|.:|..:|...:.:.|:|:.....||::....
  Rat   417 FLLNLGRKQKIPWNFQHMMMFSGL--------RGAIAFALAIRNTESQPKQMMFTTTLLLVFFTV 473

  Fly   666 IIF---TAPLGAILMLRL 680
            .:|   |.|:...|.:|:
  Rat   474 WVFGGGTTPMLTWLQIRV 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha2	NP_001247251.1	NhaP	279..>686	CDD:439796	84/408 (21%)
Slc9a9	NP_001258367.1	Na_H_Exchanger	12..541	CDD:470090	84/408 (21%)