Protein Alignment Nha2 and Nhe3

DIOPT Version :9

• Sequence 1: NP_001247251.1
• Gene: Nha2 / 42710
• FlyBaseID: FBgn0263390
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_723202.2
• Gene: Nhe3 / 33939
• FlyBaseID: FBgn0028703
• Length: 711
• Species: Drosophila melanogaster
• Alignment Length: 522
• Identity: 106/522 - (20%)
• Similarity: 180/522 - (34%)
• Gaps: 133/522 - (25%)

  Fly   235 WLY--IRSHWVNTSELVALLAIFLG---------------------------------LWAMGWV 264
            ||:  .|..|::.:.|..:..:.:|                                 ||....|
  Fly    55 WLFKHHRVSWLHETGLAVIYGLIVGAIIRYAGTSATLVHMQVEPQGVPTYSDKLPPDTLWFRYPV 119

  Fly   265 LLPEYSQPPTVIMRIAFLFVGAQISGILVTFVHL-----PDMLGMLFFGVLYANLGLANFEGYQ- 323
            .....::||..|...|::|.| |:..:....:.|     |:    :||.::..  .:..:.||.
  Fly   120 NQTNGTKPPEGIKTYAYVFRG-QVHDVDENEIDLKATFDPE----VFFNIILP--PIIFYAGYSL 177

  Fly   324 KFELFLREMALINIMLLAGLGLDGDAFKRLWFMILRLTLLPTIVEVAAIAGLANLTLSMPWLWGI 388
            |.:.|.|.:..|....:.|..|  .||....||...:.|:|..           |:.|..:|..:
  Fly   178 KKKYFFRNLGAILTFAIVGTTL--SAFLIGGFMYGCVKLMPKY-----------LSSSFTFLDSL 229

  Fly   389 ALGLVITAVSPNVVVTVMLKLKEDRLGLNSGIHTLIYAMTTCNDVVAIFMFGVIISV-------- 445
            ..|.:|:...|..::.:...|:.|     ..::.|:...:..||.|||.:.|.|.:.
  Fly   230 YFGALISPTDPLTILAIFNDLRVD-----VNLYALVLGESVLNDAVAIVLSGAIQNYGEHYSNTG 289

  Fly   446 IFSTT----SLTQQVLQGPIGIGIGLVFGYLYGSMLQYLPSRNATYANGLRFVL----------- 495
            .|.||    ||:.......:.:.||...|.|...|.::...|:........|||
  Fly   290 EFETTAFLRSLSDFFSIFLLSLMIGAAMGCLTALMTKFTRVRDFPLLESALFVLMSYSTFLLAEA 354

  Fly   496 TILGGTIAVM--GSRVIGYTSAGALGCVTTAFIARIGWRREETRLTPQQLQAQQIASVPKRLDLM 558
            |.|.|.:||:  |.....||....               .|::|...:|:           .:|:
  Fly   355 TELTGVVAVLFCGICQAHYTYNNL---------------SEDSRQRTKQI-----------FELL 393

  Fly   559 WKFLKPVSFALIGKEINFNVLQGHV-IGYGALLVLVGSLFRLAFAYLSTYGGNLSRKERAYITIS 622
            ....:...|:.||..: |...:.|. .|:.....:..::.|....|..::..|:.||.:   ..:
  Fly   394 NFLAENFIFSYIGVSM-FTFPKHHFDAGFIITAFICAAIGRAVNVYPLSWLLNIKRKPK---IST 454

  Fly   623 GFPKATVQAAL-GPVALDMARAASVASPEQLALAGNLLIISVLAIIFTAPL--GAILMLRLAPYW 684
            .|......|.| |.::..:|...:|:...|..|....||     :|||..:  ||...|.   .|
  Fly   455 NFQHMLFFAGLRGAMSFALAIRNTVSDERQTMLTATSLI-----VIFTVVIQGGAANFLL---NW 511

  Fly   685 LK 686
            ||
  Fly   512 LK 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha2	NP_001247251.1	Na_H_Exchanger	279..686	CDD:294713	92/441 (21%)
Nhe3	NP_723202.2	b_cpa1	155..>531	CDD:273294	89/421 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0025
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900