Protein Alignment Nha2 and Slc9a8

DIOPT Version :9

• Sequence 1: NP_001247251.1
• Gene: Nha2 / 42710
• FlyBaseID: FBgn0263390
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_001020452.2
• Gene: Slc9a8 / 311651
• RGDID: 1308193
• Length: 575
• Species: Rattus norvegicus
• Alignment Length: 480
• Identity: 95/480 - (19%)
• Similarity: 164/480 - (34%)
• Gaps: 160/480 - (33%)

  Fly   282 LFVGAQISGILVTFVH---------LPDMLGMLFFGVLYANL-------GLANFEGYQKFE---L 327
            :|....:..|.:..||         ||:.:.::..|:|...:       .|||::..:.|.   .
  Rat    56 IFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKVIEFKKLANWKEEEMFRPNMF 120

  Fly   328 FLREMALINIMLLAGLGL-DGDAFKRLWFMILRLTLLPTIVEVAAIA------GLANLTLSMPWL 385
            ||  :.|..|:..:|..| .|:.|:.:..:.| ..:..|.:....:.      |.|::...:...
  Rat   121 FL--LLLPPIIFESGYSLHKGNFFQNIGSITL-FAVFGTAISAFVVGGGIYFLGQADVISKLNMT 182

  Fly   386 WGIALGLVITAVSPNVVVTVMLKLKEDRLGLNSGIHTLIYAMTTCNDVVAIFM------------ 438
            ...|.|.:|:||.|...:.:...|..|.:     ::.|::..:..||.|:|.:
  Rat   183 DSFAFGSLISAVDPVATIAIFNALHVDPV-----LNMLVFGESILNDAVSIVLTNTAEGLTRKHM 242

  Fly   439 ------------FGVIISVIFSTTSLTQQVLQGPIG----------------IGIGLVFGYL-YG 474
                        .|..:.:.|.:.:|  ..|.|.|.                .|:.::|.|| ||
  Rat   243 SDVSGWQTFSQALGYFLKMFFGSAAL--GTLTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYG 305

  Fly   475 SMLQYLPSRNATYANGLRFVLTILGGTIAVMGSRVI--GYTSAGALGCVTTAFIARIGWRREETR 537
                        .|.|:.     |.|.:|::.|.::  .||                     ...
  Rat   306 ------------LAEGIS-----LSGIMAILFSGIVMSHYT---------------------HHN 332

  Fly   538 LTP--QQLQAQQIASVPKRLDLMWKFL-KPVSFALIGK---------EINFNVLQGHVIGYGALL 590
            |:|  |.|..|.:.:|        .|| :...||.:|.         ||:|.:       :..:|
  Rat   333 LSPVTQILMQQTLRTV--------AFLCETCVFAFLGLSIFSFPHKFEISFVI-------WCIVL 382

  Fly   591 VLVG---SLFRLAFAYLSTYGGNLSRKERAYITISGFPKATVQAALGPVALDMARAASVASPEQL 652
            ||.|   ::|.|::.........::.|....:..||...|.      |.||.:  ...:...|:.
  Rat   383 VLFGRAVNIFPLSYLLNFFRDHKITPKMMFIMWFSGLRGAI------PYALSL--HLGLEPMEKR 439

  Fly   653 ALAGNLLIISVLAIIF-----TAPL 672
            .|.|...||.||..|.     |.||
  Rat   440 QLIGTTTIIIVLFTILLLGGSTMPL 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha2	NP_001247251.1	Na_H_Exchanger	279..686	CDD:294713	95/480 (20%)
Slc9a8	NP_001020452.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900