Protein Alignment Nha2 and SLC9A9

DIOPT Version :9

• Sequence 1: NP_001247251.1
• Gene: Nha2 / 42710
• FlyBaseID: FBgn0263390
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_775924.1
• Gene: SLC9A9 / 285195
• HGNCID: 20653
• Length: 645
• Species: Homo sapiens
• Alignment Length: 500
• Identity: 95/500 - (19%)
• Similarity: 167/500 - (33%)
• Gaps: 158/500 - (31%)

  Fly   228 EYKGPKWWLYIRSHWVNTSELVALL-------AIFLGLWAMGWVLLPE------YSQPPTVIMR- 278
            |||..:   .|..|.:|..:..|:|       .||..      ||||.      ||.......:
Human   103 EYKYKR---EISQHNINPHQGNAILEKMTFDPEIFFN------VLLPPIIFHAGYSLKKRHFFQN 158

  Fly   279 ----IAFLFVGAQISGILVTFVHLPDMLGMLFFGVLYANLGLANFEGYQKFELFLREMALINIML 339
                :.:.|:|..||.|::         |::.:|                         .:..|:
Human   159 LGSILTYAFLGTAISCIVI---------GLIMYG-------------------------FVKAMI 189

  Fly   340 LAGLGLDGD-AFKRLWFMILRLTLLPTIVEVAAIAGLANLTLSMPWLWGIALGLVITAVSPNVVV 403
            .||...:|| .|....|                                  .|.:::|..|..|:
Human   190 HAGQLKNGDFHFTDCLF----------------------------------FGSLMSATDPVTVL 220

  Fly   404 TVMLKLKEDRLGLNSGIHTLIYAMTTCNDVVAIFMFGVIISV--------IFSTTSLTQQVLQGP 460
            .:..:|..|     ..::||::..:..||.||| :....||:        .|...:..|.|
Human   221 AIFHELHVD-----PDLYTLLFGESVLNDAVAI-VLTYSISIYSPKENPNAFDAAAFFQSV---- 275

  Fly   461 IGIGIGLVFG-YLYGSMLQYLPSRNATYANGLRFVLTILGGTIAVMGSRVIGYTSAGALGCVTTA 524
             |..:|:..| :..||....:.:....:.....|.:...|....:..|..:...:||..|.|...
Human   276 -GNFLGIFAGSFAMGSAYAIITALLTKFTKLCEFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVL 339

  Fly   525 FIARIGWRREETRLTPQQLQAQQIASVPK-RLDLMWKFL----KPVSFALIGKEINFNVLQGHVI 584
            |..          :|........::|..| |...:::|:    :.|.|..:|  :.....|.|:
Human   340 FCG----------VTQAHYTYNNLSSDSKIRTKQLFEFMNFLAENVIFCYMG--LALFTFQNHI- 391

  Fly   585 GYGALLVLVGSLFRLAFA-----YLSTYGGNLSRKERA------YITISGFPKATVQAALGPVAL 638
             :.||.:| |:...:..|     |..::..||.||::.      .:..||.        .|.:|.
Human   392 -FNALFIL-GAFLAIFVARACNIYPLSFLLNLGRKQKIPWNFQHMMMFSGL--------RGAIAF 446

  Fly   639 DMARAASVASPEQLALAGNLLIISVLAIIF---TAPLGAILMLRL 680
            .:|...:.:.|:|:.....||::.....:|   |.|:...|.:|:
Human   447 ALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWLQIRV 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha2	NP_001247251.1	Na_H_Exchanger	279..686	CDD:294713	79/430 (18%)
SLC9A9	NP_775924.1	Na_H_Exchanger	128..486	CDD:279355	85/465 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	594..622

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900