Protein Alignment Nha2 and Slc9a4

DIOPT Version :9

• Sequence 1: NP_001247251.1
• Gene: Nha2 / 42710
• FlyBaseID: FBgn0263390
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: XP_006244800.1
• Gene: Slc9a4 / 24785
• RGDID: 3721
• Length: 797
• Species: Rattus norvegicus
• Alignment Length: 486
• Identity: 98/486 - (20%)
• Similarity: 175/486 - (36%)
• Gaps: 151/486 - (31%)

  Fly   236 LYIR-SHWVNTSELVALLAIFLGLWAMGWVLLPEYSQPPTVIMRIAFLFVGAQISGILVTFVHLP 299
            ||.| .|.:..|.|:.::...:|....|    ..:..||.:...|.||::...|  :|.:...:|
  Rat    89 LYHRLPHLMPESCLLIIVGALVGSIIFG----THHKSPPVMDSSIYFLYLLPPI--VLESGYFMP 147

  Fly   300 -----DMLGMLFFGVLYANLGLANFEGYQKFELFLREMALINIMLLAGLGLDGDAFKRLWFMILR 359
                 :.:|.:.:   :|.||                 ||||..   |:||.      |:|
  Rat   148 TRPFFENIGSILW---WAGLG-----------------ALINAF---GIGLS------LYF---- 179

  Fly   360 LTLLPTIVEVAAIAGLANLTLSMPWLWGIALGLVITAVSPNVVVTVMLKLKEDRLGLNSGIHTLI 424
                  |.::.|. ||.::.|    |..:..|.:|:||.|   |.|:...:|.|  :|..::.:|
  Rat   180 ------ICQIKAF-GLGDINL----LQNLLFGSLISAVDP---VAVLAVFEEAR--VNEQLYMMI 228

  Fly   425 YAMTTCNDVVAIFMFGVIIS-----------VIFSTTSLTQQVLQGPIGIGIGLVFGYLYGSMLQ 478
            :.....||.:::.::.::|:           .:.......:.|:.|..|:..|::||::...:.:
  Rat   229 FGEALLNDGISVVLYNILIAFTKMHKFEDIEAVDILAGCARFVIVGCGGVFFGIIFGFISAFITR 293

  Fly   479 YLPSRNA---------TYANGLRFVLTILGGTIAVMGSRV------------------------- 509
            :..:.:|         :|.:.|......|.|.:|:....|
  Rat   294 FTQNISAIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKML 358

  Fly   510 -----------IGYTSAG-------ALGCVTTAFIARIGWR----------REETRLTPQQLQAQ 546
                       :|.::.|       |..|.|.|| .:| ||          ..:.|..|..::.|
  Rat   359 SSVSETLIFIFMGVSTVGKNHEWNWAFVCFTLAF-CQI-WRAISVFTLFYVSNQFRTFPFSIKDQ 421

  Fly   547 QI---ASVPKRLDLMWKFLKPVSFALIGKEINFNVLQGHVIGYGALL---VLVGSLFRLAFAYLS 605
            .|   :.|.........||.|:|  |..::..| |....|:.|..:.   :.:|.|.|    ||.
  Rat   422 LIIFYSGVRGAGSFSLAFLLPLS--LFPRKKLF-VTATLVVTYFTVFFQGITIGPLVR----YLD 479

  Fly   606 TYGGNL--SRKERAYITISGFPKATVQAALG 634
            ....|.  |..|..:|.:....||.::...|
  Rat   480 VRKTNKKESINEELHIRLMDHLKAGIEDVCG 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha2	NP_001247251.1	Na_H_Exchanger	279..686	CDD:294713	88/442 (20%)
Slc9a4	XP_006244800.1	b_cpa1	63..621	CDD:273294	98/486 (20%)
		Na_H_Exchanger	73..476	CDD:279355	88/446 (20%)
		NEXCaM_BD	569..675	CDD:293250

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900