Protein Alignment Nha2 and Slc9a3

DIOPT Version :10

• Sequence 1: NP_001247251.1
• Gene: Nha2 / 42710
• FlyBaseID: FBgn0263390
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: XP_038956774.1
• Gene: Slc9a3 / 24784
• RGDID: 3720
• Length: 864
• Species: Rattus norvegicus
• Alignment Length: 534
• Identity: 105/534 - (19%)
• Similarity: 188/534 - (35%)
• Gaps: 142/534 - (26%)

  Fly   233 KWWLYIRSHWVNTSELVALLAIFLGLWAMGWVLLPEYSQPPTVIMRIAFLFVGAQISGILVTFVH 297
            ||      |.|....::||           |:|:..       :.:|.| .:..:::.:
  Rat    45 KW------HHVQDPYIIAL-----------WILVAS-------LAKIVF-HLSHKVTSV------ 78

  Fly   298 LPD-----MLGMLFFGVLYANLGLANFEGYQKFELFLREMALINIMLLAGLGLDGDAF--KRLWF 355
            :|:     :||::..|:::|...:|:         |.....|....||..:.||...|  .||:|
  Rat    79 VPESALLIVLGLVLGGIVWAADHIAS---------FTLTPTLFFFYLLPPIVLDAGYFMPNRLFF 134

  Fly   356 MILRLTLLPTIVEV---AAIAGLANLTLSMPWLWG---------IALGLVITAVSPNVVVTVMLK 408
            ..|...||..::..   ||..||:...:.:..|.|         :..|.:|.||.|..|:.|.
  Rat   135 GNLGTILLYAVIGTIWNAATTGLSLYGVFLSGLMGELKIGLLDFLLFGSLIAAVDPVAVLAVF-- 197

  Fly   409 LKEDRLGLNSGIHTLIYAMTTCNDVVAIFMFGVIIS------------------VIFSTTSLTQQ 455
               :.:.:|..:..:::..:..||.|.:.::.|..|                  |.|...||.
  Rat   198 ---EEVHVNEVLFIIVFGESLLNDAVTVVLYNVFESFVTLGGDAVTGVDCVKGIVSFFVVSLG-- 257

  Fly   456 VLQGPIGIGIGLVFGYLYGSMLQYLPSRNATYANGLRFVLTILGGTIAVM--GSRVIGYTSAGAL 518
                  |..:|::|.:|. |::............|..||::.|....:.|  .|.::..|..|.
  Rat   258 ------GTLVGVIFAFLL-SLVTRFTKHVRIIEPGFVFVISYLSYLTSEMLSLSAILAITFCGI- 314

  Fly   519 GCVTTAFIARIGWRREETRLTPQQLQAQQIASVPKRLDLMWKFLKPVSFALIGKEINFNVLQGHV 583
             |......|.|    .|...|..:...:.:||..:.:..|:..:..|...:......|.:|
  Rat   315 -CCQKYVKANI----SEQSATTVRYTMKMLASGAETIIFMFLGISAVDPVIWTWNTAFVLL---- 370

  Fly   584 IGYGALLVLVGSLFRLAFAYLSTYGGN------LSRKERAYITISGFPKATVQAALGPVALDMAR 642
                 .||.: |::|.....|.|:..|      |...::..::..|...|...|.:  |.||
  Rat   371 -----TLVFI-SVYRAIGVVLQTWILNRYRMVQLETIDQVVMSYGGLRGAVAYALV--VLLD--- 424

  Fly   643 AASVASPEQLALAGNLLIISVLAIIFTAPLGAILMLRLAPYWLK---------------HGDAVE 692
                   |:.....||.:.:.|.::|...:...|.::....|||               ||.|.:
  Rat   425 -------EKKVKEKNLFVSTTLIVVFFTVIFQGLTIKPLVQWLKVKRSEQREPKLNEKLHGRAFD 482

  Fly   693 AVDSPTTPIAPTLG 706
            .:.|....|:..:|
  Rat   483 HILSAIEDISGQIG 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha2	NP_001247251.1	NhaP	279..>686	CDD:439796	89/451 (20%)
Slc9a3	XP_038956774.1	b_cpa1	45..644	CDD:273294	105/534 (20%)