Protein Alignment Nha2 and nhx-1

DIOPT Version :9

• Sequence 1: NP_001247251.1
• Gene: Nha2 / 42710
• FlyBaseID: FBgn0263390
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_510622.3
• Gene: nhx-1 / 181680
• WormBaseID: WBGene00003729
• Length: 514
• Species: Caenorhabditis elegans
• Alignment Length: 469
• Identity: 94/469 - (20%)
• Similarity: 186/469 - (39%)
• Gaps: 110/469 - (23%)

  Fly   268 EYSQP--PTVIMRIAFLFVGAQISGILVTFVHLPDMLGMLFFGVLYANLGLANFEGYQKFELFLR 330
            ::::|  ||::.....|.|||:|.     |..:|..........:...|||  |.|:..:||:..
 Worm     8 QWNRPETPTLLGLWLLLIVGAKIG-----FHRMPRARHFFPESAVLIVLGL--FAGFTIYELWTV 65

  Fly   331 EM----------ALINIMLLAGLGLDGDAFKRLWFMILRLTLLPTIVEVAAIAG-LANLTLSMPW 384
            ::          .|..|:|.||..:...||      |..:    |.:.:.|:|| :.|:.|:..:
 Worm    66 DLFLHPDLFFLYLLPPIVLEAGYFMPNKAF------ISNI----TTISLFAVAGTVMNIFLTSCF 120

  Fly   385 LWG--------------IALGLVITAVSPNVVVTVMLKLKEDRLGLNSGIHTLIYAMTTCNDVVA 435
            ::.              :....||:||.|..|::|.     :.:.:|..::..::..:..||.|.
 Worm   121 IFAFQNFYDFNITIVDTLLFSTVISAVDPVAVLSVF-----EEIHVNKLLYITVFGESLLNDAVT 180

  Fly   436 IFMFGVIISVI----------FSTTSLTQQVLQGPIGIGIGLVFGYLYGSMLQYLPSRNATYANG 490
            :.::....|::          ..|.|:....|....||.:|:||..:....:::  |.|.:.
 Worm   181 VVLYHSFHSMVRIGQAHLIYQDYTMSMMNFFLVSGGGILVGVVFAVVAALGVKW--SSNVSV--- 240

  Fly   491 LRFVLTILGGTIAVMGSRVIGYTSAGALGCVTTAFIARIGWRREETRLTPQQLQAQQIASVPKRL 555
            |:.::.|....:|.:.|.::..  :|.||.|.....                :::....|:.:|.
 Worm   241 LQPIICITVPYMAYLCSEIVHV--SGILGIVVCGLC----------------MKSYVTGSMEERA 287

  Fly   556 DLMWKF-LKPVSF---ALIGKEINFNVL-QGHVIGYGALLVLVGSLF--RLAFAYLSTYGGNLSR 613
            |:..|: ||.:|.   |:|...:.|::. :.|...:|..:|.|.:.|  |....:..|:..|..|
 Worm   288 DITVKYTLKTLSSCCEAIIFVFLGFSIFSKDHKWDFGFAIVTVITCFAARFLVVFTLTWVANKWR 352

  Fly   614 KERAYI---TISGFPKATVQAALGPV-ALDMARAASVASPEQLALAGNLLIISVLAIIFTA---- 670
            .::..:   ||..|.........|.| .:|    ..|...:.:.::..|::     |:||.
 Worm   353 MQKISLRDQTIMAFGGLRGAICFGLVLTID----GEVVPAKPIMISTTLIV-----IVFTVFIQG 408

  Fly   671 ----PLGAILMLRL 680
                ||.:.|.:::
 Worm   409 TMIKPLVSFLNVKI 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha2	NP_001247251.1	Na_H_Exchanger	279..686	CDD:294713	91/456 (20%)
nhx-1	NP_510622.3	Na_H_Exchanger	43..415	CDD:279355	82/420 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900