Protein Alignment Nha2 and pbo-4

DIOPT Version :9

• Sequence 1: NP_001247251.1
• Gene: Nha2 / 42710
• FlyBaseID: FBgn0263390
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_509830.2
• Gene: pbo-4 / 181285
• WormBaseID: WBGene00003943
• Length: 783
• Species: Caenorhabditis elegans
• Alignment Length: 495
• Identity: 96/495 - (19%)
• Similarity: 180/495 - (36%)
• Gaps: 130/495 - (26%)

  Fly   227 DEYKG---PKW-WLYIRSHWVNTSELVALLAIFLGLWAMGW-------VLLPEYSQPPTVIMRIA 280
            ||..|   ..| |.|:::..|.|     |..|.:||:.:.:       .:|||         ...
 Worm    89 DESHGISVVSWHWDYVKNELVLT-----LFFIVIGLFKLVYHHTFVTRKILPE---------SCC 139

  Fly   281 FLFVGAQISGILVTFVHLPDMLGMLFFG-VLYANLGLANFEGYQKFELFLREMALINIMLLAGLG 344
            .:|:|..|              |..|.| ..:|::....|:. :.|..:|    |..|:|.:...
 Worm   140 LIFIGIAI--------------GFFFVGDATHASIKFLEFKS-KVFFFYL----LPPIILESAYS 185

  Fly   345 LDGDAFKRLWFMILRLTLLPTIVEVAAIAGLANLTLSMPWLWG---------IALGLVITAVSPN 400
            |...||......||...::.||:.:..:|. |.|.|....:.|         :....::.||.|.
 Worm   186 LKDRAFIENIGTILLYAVVGTILNIVLLAA-ALLILIWVGIMGKYNLSVMDILTFASLVAAVDPV 249

  Fly   401 VVVTVMLKLKEDRLGLNSGIHTLIYAMTTCNDVVAIFMFGVIISVIFSTTSLTQQVLQGP----- 460
            .|:.|.     ..:|:|..::.:::..:..||.|.|..:.:.|.  |.|.         |
 Worm   250 AVLAVF-----QEVGVNKMLYFMVFGESLFNDAVTIVCYNLAIE--FQTL---------PDFTWY 298

  Fly   461 -----------IGIGIGLVFGYLYGSMLQYLPSRNATYANGLRFV--LTILG-GTIAVMGSRVIG 511
                       :.|| ||:.|.:.|::..::    ..:...:|.|  :.:.| ..:|.:||.:..
 Worm   299 HGFLGLLSFLCVSIG-GLIIGLICGAISSFV----TKFTTDVRVVEPVVLFGMAYLAYLGSEMFH 358

  Fly   512 YTSAGALGCVTTAFIARIGWRREETRLTPQQLQAQQIASVPKRLDLMWKFLKPVSFALIG----K 572
            :          :..||.|.....:|......:..:...||.....:.....:.:.|.::|    .
 Worm   359 F----------SGIIALIACGLFQTHYACCNISYKSFTSVMYITKVCSTLCESLIFIILGVMLVN 413

  Fly   573 EINFNVLQGHVIGYGALLVLVGSLFRLAFAYLSTY------GG--NLSRKERAYITISGFPKATV 629
            |..:.....|.: :.|:.|::..:.|....:..||      ||  ::|.:|:..::..|.
 Worm   414 EREWFWTDWHPV-FSAVSVVLCVVVRFGVTFFLTYFVNQFTGGVRHISFQEQFIMSYGGL----- 472

  Fly   630 QAALGPVALDMARAASVASPEQLALAGNLLIISVLAIIFT 669
               .|.|:..:....| |:|:   :...:|..:...|:||
 Worm   473 ---RGAVSFSLVFMIS-ANPD---VKNTMLGATYAVILFT 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha2	NP_001247251.1	Na_H_Exchanger	279..686	CDD:294713	81/432 (19%)
pbo-4	NP_509830.2	Na_H_Exchanger	115..519	CDD:279355	87/464 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900