Protein Alignment Nha2 and slc-9B.2

DIOPT Version :9

• Sequence 1: NP_001247251.1
• Gene: Nha2 / 42710
• FlyBaseID: FBgn0263390
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_507130.2
• Gene: slc-9B.2 / 180097
• WormBaseID: WBGene00010214
• Length: 498
• Species: Caenorhabditis elegans
• Alignment Length: 455
• Identity: 113/455 - (24%)
• Similarity: 208/455 - (45%)
• Gaps: 38/455 - (8%)

  Fly   265 LLPEYSQPP-----------TVIMRIAFLFVGAQISGILVTFVHLPDMLGMLFFGVLYANLG-LA 317
            |.|.::.||           |.|  |..|..|...:......:.||.:.|.|..|::..|:. |.
 Worm    39 LTPLHAIPPGAPSENKTVKSTFI--IFLLLFGGLFAAKSSNALRLPPLFGCLALGIVIRNVDVLK 101

  Fly   318 NFEGYQKF-ELFLREMALINIMLLAGLGLDGDAFKRLWFMILRLTLLPTIVEVAAIAGLANLTLS 381
            :|.....| |..:|::||..|::..||..|...........:.:.|:..|.|:.||...:.|.|.
 Worm   102 DFFIIPPFTETMIRKVALAMIVIRWGLATDVKFLYENAVTPVTIGLVTAIGEIIAITIASFLILD 166

  Fly   382 MPWLWGIALGLVITAVSPNVVVTVMLKLKEDRLGLNSGIHTLIYAMTTCNDVVAIFMFGVIISVI 446
            :.::..:...|::..|||.|.|..|:..||..||.:..|...:.|:...:::..:.:|.|:.|:|
 Worm   167 ISFVMAVFCALILVIVSPAVTVPAMISFKERGLGSSKRIPENVLAVCCVDNLFCVIVFMVLSSII 231

  Fly   447 FSTTSLTQQVLQGPIGIGIGLVFGYLYGSMLQYLPSRNATYANGLRFVLTILG-GTIAVM-GSRV 509
            |:...:...:|.....|.:|.:.|.:.|.:|...|..:.|:....|  :|:|| ..|.:| |:.:
 Worm   232 FTDAPIATTILMNAGSILLGCIGGIIIGLLLWRFPRPDTTHTQFAR--ITLLGTSCIGLMIGTYL 294

  Fly   510 IGYTSAGALGCVTTAFIARIGWRREETRLTPQQLQAQQIASVPKRLDLMW-KFLKPVSFALIGKE 573
            :.|:.||.|..:.|:.:..:.|:.:         ...::..|......:| .|..|:.|..:|.:
 Worm   295 VKYSCAGFLAALITSSMCAMKWKTD---------NKDKLDCVVSTYKYVWDSFALPLLFICLGLK 350

  Fly   574 INFNVLQGHVIGYGALLVLVGSLFRLAFAYLSTYGGNLSRKERAYITISGFPKATVQAALGPVAL 638
            .:|:.|...::.....::.:|.:.|.....|:|:..:.:.||:|.|.:|..|:||.||.|.|..:
 Worm   351 FDFSTLSWKIVLLCISVICIGLIVRALLVMLTTHFSHFNVKEKAVIALSLLPRATFQADLAPTLV 415

  Fly   639 DMARAASVASPEQLALAGNLLIISVLAIIFTAPLGAILMLRLAPYWLKH-----GDAVEAVDSPT 698
            .||    ...|::|..|..::..::|:::.|||:..||:..:...:|.|     ..|:|..:.||
 Worm   416 VMA----TPFPDKLPDAELVMKAAILSVLITAPIFDILLNLIGSKFLYHVLPQEDVALENNEVPT 476

  Fly   699  698
             Worm   477  476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha2	NP_001247251.1	Na_H_Exchanger	279..686	CDD:294713	101/411 (25%)
slc-9B.2	NP_507130.2	Na_H_Exchanger	59..411	CDD:382399	90/364 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159331
Domainoid	1	1.000	137	1.000	Domainoid score	I3031
eggNOG	1	0.900	-	-		E1_COG0025
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	151	1.000	Inparanoid score	I2955
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D406317at33208
OrthoFinder	1	1.000	-	-		FOG0001578
OrthoInspector	1	1.000	-	-		mtm4756
orthoMCL	1	0.900	-	-		OOG6_103025
Panther	1	1.100	-	-	O	PTHR31102
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4408
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.790