Protein Alignment Nha2 and Nha1

DIOPT Version :10

• Sequence 1: NP_001247251.1
• Gene: Nha2 / 42710
• FlyBaseID: FBgn0263390
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: XP_061496802.1
• Gene: Nha1 / 1281378
• VectorBaseID: AGAMI1_000233
• Length: 654
• Species: Anopheles gambiae
• Alignment Length: 505
• Identity: 166/505 - (32%)
• Similarity: 261/505 - (51%)
• Gaps: 44/505 - (8%)

  Fly   228 EYKGPKW----WLYIRSH-----WVNTSELVALLAIFLGLWAMGWVLLPEYSQPPTVIMRIAFLF 283
            ||..|.|    |..:..:     :...:.:::::.|.:.||...:|::.:.:.|...:.::..|.
Mosquito   130 EYTTPSWEPPGWQKVCPYPLCPSYRQFARILSIILIGVLLWITAFVIIGDTAAPGGQLFQLVVLT 194

  Fly   284 VGAQISGILVTFVHLPDMLGMLFFGVLYANLGLANFEG-YQKFELFLREMALINIMLLAGLGLDG 347
            |.|...|.|::...||.::|||..|:|:.|:|..|.:| :|.....||::||:.|::.|||.:|.
Mosquito   195 VAANFGGFLISLTTLPRLIGMLMVGILFQNVGWVNLDGEFQIVTAELRKLALVIILIRAGLEMDP 259

  Fly   348 DAFKRLWFMILRLTLLPTIVEVAAIAGLANLTLSMPWLWGIALGLVITAVSPNVVVTVMLKLKED 412
            .|||:::..||:|.|:|..||.:.||..|...|.:||:|.|.||.::.||||.|||..:.:|:..
Mosquito   260 TAFKKIYKTILKLGLIPWFVECSLIAVCARFFLQLPWMWSILLGSIVGAVSPAVVVPCLFRLRTK 324

  Fly   413 RLGLNSGIHTLIYAMTTCNDVVAIFMFGVIISVIFSTTSLTQQVLQGPIGIGIGLVFGYLYGSML 477
            ..|:..||.|||.|:...:|.|::..||:|.|::|||.||..|:.|.|:.|..||.||.::|.:.
Mosquito   325 GYGVVKGIPTLIIAVAGIDDAVSVAGFGIISSIMFSTQSLGLQIAQAPVCIIGGLGFGVVWGFLC 389

  Fly   478 QYLPSRNATYANGLRFVLTILGGTIAVMGSRVIGYTSAGALGCVTTAFIARI-----GWRREETR 537
            :|:|.....|...:|.::...||.:||.||..|.:..||.||.|..||.|..     ||..|:.
Mosquito   390 KYVPEPGDAYVVPIRTLMLFGGGLLAVFGSEEIHFEGAGPLGVVFAAFTASYFWCGQGWELEDN- 453

  Fly   538 LTPQQLQAQQIASVPKRLDLMWKFLKPVSFALIGKEINFNVLQGHVIGYGALLVLVGSLFRLAFA 602
                        .|....::.|...:|:.|.:.|..|....|..|::..|     |||::.:|..
Mosquito   454 ------------PVSTAFEIFWMIFEPILFGITGASIKIAELDPHIVSIG-----VGSIYAVAVI 501

  Fly   603 YLST-----YGGNLSRKERAYITISGFPKATVQAALGPVALDMARAASVASPEQLALAGNLLIIS 662
            .:.|     :|..|:.||:.::.||...|||||||||||||....:....:.|::..|..:.::.
Mosquito   502 RILTTVAIAFGDKLNVKEKIFVAISWMSKATVQAALGPVALKTVMSNENRTEEEVHYAELVKMVC 566

  Fly   663 VLAIIFTAPLGAILMLRLAPYWLKHGDAVEAVDSPTTPIAPTLGSTNSSK 712
            :|:||.||||||||:.......||      .......|:..|||...|.:
Mosquito   567 ILSIILTAPLGAILISVTGTKLLK------KTKQQLEPLDGTLGWRRSHR 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nha2	NP_001247251.1	NhaP	279..>686	CDD:439796	149/417 (36%)
Nha1	XP_061496802.1	None